Results 261 to 270 of about 93,899 (311)
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Drugs, 2003
The excellent tolerability of therapeutic doses of paracetamol (acetaminophen) is a major factor in the very wide use of the drug. The major problem in the use of paracetamol is its hepatotoxicity after an overdose. Hepatotoxicity has also been reported after therapeutic doses, but critical analysis indicates that most patients with alleged toxicity ...
Garry G, Graham +2 more
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The excellent tolerability of therapeutic doses of paracetamol (acetaminophen) is a major factor in the very wide use of the drug. The major problem in the use of paracetamol is its hepatotoxicity after an overdose. Hepatotoxicity has also been reported after therapeutic doses, but critical analysis indicates that most patients with alleged toxicity ...
Garry G, Graham +2 more
openaire +3 more sources
Journal of Pharmaceutical Sciences, 2018
The objective was to study the relationship between crystal structure, particle deformation properties, and tablet-forming ability for the monoclinic form of paracetamol (PRA), 2 cocrystals and a salt crystal of PRA in addition to 2 coformers (oxalic acid and 4,4'-bipyridine).
Ann-Sofie, Persson +3 more
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The objective was to study the relationship between crystal structure, particle deformation properties, and tablet-forming ability for the monoclinic form of paracetamol (PRA), 2 cocrystals and a salt crystal of PRA in addition to 2 coformers (oxalic acid and 4,4'-bipyridine).
Ann-Sofie, Persson +3 more
openaire +2 more sources
Expert Opinion on Pharmacotherapy, 2003
Paracetamol (acetaminophen) is one of the over-the-counter analgesics that is used frequently for the self-management of some of the common disorders. There seems to be two types of relations between paracetamol and asthma - paracetamol intolerance leading to bronchospasm in analgesic-induced asthmatics; and the relation between asthma and the amount ...
Kalyoncu, AF, Karakaya, G
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Paracetamol (acetaminophen) is one of the over-the-counter analgesics that is used frequently for the self-management of some of the common disorders. There seems to be two types of relations between paracetamol and asthma - paracetamol intolerance leading to bronchospasm in analgesic-induced asthmatics; and the relation between asthma and the amount ...
Kalyoncu, AF, Karakaya, G
openaire +3 more sources
Legal Limits for Paracetamol Sales
Lancet, The, 2007 In Ireland, there were 7933 recorded cases of drug overdose in 2004, of which 31% involved paracetamol.4 It is against the law for pharmacies in Ireland to sell more than 24 paracetamol (500 mg) tablets in a single transaction.5 In early 2007, we visited
Patricia Casey, Brendan D. Kelly
exaly +2 more sources
Clinical & Experimental Allergy, 1992
SummaryWe describe four cases of anaphylaxis to paracetamol without co‐existing aspirin intolerance and review the Australian experience in paracetamol anaphylaxis. Paracetamol sensitivity may differ in the mechanism from sensitivity to aspirin and other non‐steroidal anti‐inflammatory drugs as previously believed.
R, Leung, R, Plomley, D, Czarny
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SummaryWe describe four cases of anaphylaxis to paracetamol without co‐existing aspirin intolerance and review the Australian experience in paracetamol anaphylaxis. Paracetamol sensitivity may differ in the mechanism from sensitivity to aspirin and other non‐steroidal anti‐inflammatory drugs as previously believed.
R, Leung, R, Plomley, D, Czarny
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Drugs, 2003
The orally administered fixed combination tablet of tramadol (centrally-acting opiate) plus paracetamol (acetaminophen; nonopiate, nonsalicylate analgesic) [37.5/325 mg] provides effective analgesia in patients with moderate to severe acute pain and those with chronic painful conditions characterised by intermittent exacerbations of pain.
Karen, McClellan, Lesley J, Scott
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The orally administered fixed combination tablet of tramadol (centrally-acting opiate) plus paracetamol (acetaminophen; nonopiate, nonsalicylate analgesic) [37.5/325 mg] provides effective analgesia in patients with moderate to severe acute pain and those with chronic painful conditions characterised by intermittent exacerbations of pain.
Karen, McClellan, Lesley J, Scott
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British Journal of Nursing, 1993
It is easier than we may think to overdose inadvertently on paracetamol. With another winter upon us, many cold remedy products now carry a manufacturer's warning; however, do nurses themselves fully understand why paracetamol can be so fatal?
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It is easier than we may think to overdose inadvertently on paracetamol. With another winter upon us, many cold remedy products now carry a manufacturer's warning; however, do nurses themselves fully understand why paracetamol can be so fatal?
openaire +2 more sources
Accident and Emergency Nursing, 1997
Paracetamol is a common cause of fatal self-poisoning in the UK every year. Despite this, it continues to be sold freely without medical supervision and can be found in quantity in most household medicine cabinets.
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Paracetamol is a common cause of fatal self-poisoning in the UK every year. Despite this, it continues to be sold freely without medical supervision and can be found in quantity in most household medicine cabinets.
openaire +3 more sources
Antipyretic effects of nimesulide, paracetamol and ibuprofen-paracetamol
The Indian Journal of Pediatrics, 2000The antipyretic effect of nimesulide has not been adequately compared with paracetamol and ibuprofen-paracetamol combination in children. Hence, a randomized, double blind, and parallel groups' design and multicenter study was conducted on children with respiratory tract infections.
A, Lal, S, Gomber, B, Talukdar
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European Journal of Clinical Pharmacology, 1984
The SUR 2647 combination is a sachet formulation containing free paracetamol and its N-acetyl-methionate ester (SUR 2647). In a randomized, single-blind, between-patient study the onset of analgesia, duration and efficacy of the SUR 2647 combination vs paracetamol was investigated in out-patients after oral surgery.
L A, Skoglund, P, Skjelbred
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The SUR 2647 combination is a sachet formulation containing free paracetamol and its N-acetyl-methionate ester (SUR 2647). In a randomized, single-blind, between-patient study the onset of analgesia, duration and efficacy of the SUR 2647 combination vs paracetamol was investigated in out-patients after oral surgery.
L A, Skoglund, P, Skjelbred
openaire +2 more sources