Results 91 to 100 of about 11,391 (207)

Extracellular Vesicles From Fungal Infection in Humans: A Key Player in Immunological Responses

Journal of Extracellular Biology, Volume 4, Issue 8, August 2025.
ABSTRACT Fungal infections cause approximately 1.6 million deaths annually. Diagnosing and treating fungal infections is difficult due to limited access to diagnostic tests and rising antifungal resistance. Extracellular vesicles (EVs) facilitate interactions between fungal cells and hosts, significantly influencing the pathogen‐host relationship ...
Caroline P. de Rezende, Patrick W. S. Santos, Renan A. Piraine, Virgínia C. Silvestrini, Julio C. J. Barbosa, Fabiana C. P. Valera, Edwin Tamashiro, Guilherme G. Podolski‐Gondim, Silvana M. Quintana, Rodrigo Calado, Roberto Martinez, Taicia P. Fill, Márcio L. Rodrigues, Fausto Almeida   +13 more
wiley   +1 more source

Paracoccidioidomicose do sistema nervoso central: análise de 13 casos [PDF]

, 2006
Paracoccidioidomycosis (PCM) is a systemic granulomatous disease caused by Paracoccidioides brasiliensis, prevalent in Latin America, particularly in Brazil. Central nervous system (CNS) involvement occur in about 10% of cases. Thirteen patients with PCM
Carvalho, Gervasio Teles Cardoso, Fagundes-Pereyra, Walter J., Góes, Alfredo de Miranda, Silva, Francisco das Chagas Lima e, Sousa, Atos Alves de   +4 more
core   +3 more sources

Climate Change, Natural Disasters, and Cutaneous Fungal Infections

International Journal of Dermatology, Volume 64, Issue 8, Page 1349-1355, August 2025.
ABSTRACT Fungal infections are an important source of morbidity and mortality that can manifest as superficial or invasive diseases. Diagnostic techniques for human fungal pathogens remain problematic, and multi‐drug resistance is emerging. This review addresses the potential emergence of new fungal pathogens in changing environments and reported ...
Aditya K. Gupta, Mary Thornbush, Tong Wang   +2 more
wiley   +1 more source

Genome size and ploidy of Paracoccidioides brasiliensis reveals a haploid DNA content: Flow cytometry and GP43 sequence analysis [PDF]

, 2007
The aim of this study was to evaluate genome size and ploidy of the dimorphic pathogenic fungus Paracoccidioides brasiliensis. The cell cycle analysis of 10 P. brasiliensis isolates by flow cytometry (FCM) revealed a genome size ranging from 26.3+/-0.1Mb
Almeida, A. J., Carmona, J. A., Leão, Cecília, Ludovico, Paula, Martins, M., Matute, D. R., McEwen, J. G., Restrepo, A., Rodrigues, Fernando José dos Santos, Torres, I.   +9 more
core   +1 more source

59Fe Uptake Assays in Paracoccidioides Species

BIO-PROTOCOL, 2016
Iron is an essential micronutrient required for virtually all organisms. This fact is related to the ability of the transition metal to exist in two oxidation states, the reduced ferrous (Fe2+) and the oxidized ferric (Fe3+). Given the relative availability of aqueous iron (the element which constitutes ~5% of the earth’s crust) one is not surprised ...
Daniel Kosman, Elisa Flávia Bailão, Mirelle Silva-Bailão, Célia Maria Soares   +3 more
openaire   +2 more sources

A steric gate prevents mutagenic dATP incorporation opposite 8‐oxo‐deoxyguanosine in mitochondrial DNA polymerases

The FEBS Journal, Volume 292, Issue 13, Page 3430-3448, July 2025.
Reactive oxygen species induce mutagenic DNA lesions, such as 8‐oxo‐2′‐deoxyguanosine (8‐oxodG), which acts as a template for dCMP and dAMP incorporation through its anti and syn conformations. Specific residues must regulate the fidelity of templated 8‐oxodG.
Noe Baruch‐Torres, Carlos H. Trasviña‐Arenas, Alexandru Ionut Gilea, Upeksha C. Dissanayake, Missael Molina‐Jiménez, Paola L. García‐Medel, Corina Díaz‐Quezada, Tiziana Lodi, G. Andrés Cisneros, Enrico Baruffini, Luis G. Brieba   +10 more
wiley   +1 more source

ParaDB: A manually curated database containing genomic annotation for the human pathogenic fungi Paracoccidioides spp.

PLoS Neglected Tropical Diseases, 2019
BackgroundThe genus Paracoccidioides consists of thermodymorphic fungi responsible for Paracoccidioidomycosis (PCM), a systemic mycosis that has been registered to affect ~10 million people in Latin America.
David Aciole Barbosa, Fabiano Bezerra Menegidio, Valquíria Campos Alencar, Rafael S Gonçalves, Juliana de Fátima Santos Silva, Renata Ozelami Vilas Boas, Yara Natércia Lima Faustino de Maria, Daniela Leite Jabes, Regina Costa de Oliveira, Luiz R Nunes   +9 more
doaj   +1 more source

Destructive genital and oral ulcers in rural patients

JAAD Case Reports, 2021
Eduardo Mastrangelo Marinho Falcão, MD, MS, Priscila Marques de Macedo, MD, PhD, Dayvison Francis Saraiva Freitas, MD, PhD, Ziadir Francisco Coutinho, MD, PhD, Leonardo Pereira Quintella, MD, PhD, Rodrigo Almeida-Paes, PhD, Rosely Maria Zancopé-Oliveira, PhD, Antonio Carlos Francesconi do Valle, MD PhD   +7 more
doaj   +1 more source

Paracoccidiomicosis en el sistema nervioso central: reporte de un caso

Revista Peruana de Medicina Experimental y Salud Pública
La paracoccidiomicosis es una enfermedad micótica que puede comprometer el sistema nervioso central (SNC). Se presenta el caso de un paciente varón de 45 años, inmunocompetente, de la ciudad de Satipo, que desarrollo paracoccidiomicosis en el SNC sin ...
Jesús Rojas-Jaimes, Raul Castillo Cordova, Delza Tárraga Gonzales   +2 more
doaj  

Biochemical responses in mice experimentally infected with Paracoccidioides brasiliensis and treated with Canova

Brazilian Archives of Biology and Technology, 2006
The objective of this work was to evaluate biochemical parameters in Paracoccidioides brasiliensis infected mice and the effect of Canova medicine on these parameters.
Gisele Takahachi, Márcia Luzia Ferrarezi Maluf, Terezinha Inez Estivalet Svidzinski, Luciene Setsuko Akimoto-Günther, Márcia Rosangela Neves de Oliveira Hübler, Ciomar Aparecida Bersani-Amado, Roberto Kenji Nakamura Cuman   +6 more
doaj   +1 more source