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The pathobiology of Paracoccidioides brasiliensis

Trends in Microbiology, 2002
Paracoccidioides brasiliensis causes one of the most prevalent systemic mycoses in Latin America--paracoccidioidomycosis. It is a dimorphic fungus that undergoes a complex transformation in vivo, with mycelia in the environment producing conidia, which probably act as infectious propagules upon inhalation into the lungs, where they transform to the ...
Adrian R Walmsley
exaly   +3 more sources

Ornithine decarboxylase in Paracoccidioides brasiliensis

Archives of Microbiology, 1996
Ornithine decarboxylase in Paracoccidioides brasiliensis, a dimorphic human pathogenic fungus, was more active at 37 degrees C in the yeast phase and at 30 degrees C in the mycelial phase. In contrast to other fungal systems, yeast growth and mycelium-to-yeast transition in P.
G, San-Blas   +3 more
openaire   +2 more sources

Aleuriospores of Paracoccidioides brasiliensis

Mycopathologia, 1971
In soil extract agar and in Bennett medium abundant aleuriospores ofParacoccidioides brasiliensis have been observed. The possibility that these spores could be the infecting elements for man is discussed.
openaire   +2 more sources

Isoenzyme profile ofParacoccidioides brasiliensis

Medical Mycology, 1995
Isoenzyme profiles of 10 strains of Paracoccidioides brasiliensis from different origins (nine strains from patients with different clinical forms of paracoccidioidomycosis and one from the faeces of a penguin) were determined by polyacrylamide gel electrophoresis using 37 different enzymes.
T I, Svidzinsky, Z P, Camargo
openaire   +2 more sources

Cytosolic Neutral Proteinases of Paracoccidioides brasiliensis

Current Microbiology, 1998
Cytosolic proteinases were assayed in both morphological phases of Paracoccidioides brasiliensis. Preparations from the mycelial phase were more active in vitro than those from the yeast cells. Optimal proteinase activities for both phases occurred at pH's between 6.0 and 9.0, and at 45 degrees C.
G, San-Blas   +4 more
openaire   +2 more sources

Blastomyces (Paracoccidioides) brasiliensis in Africa

Nature, 1964
SINCE the discovery of “South American Blastomycosis” by Adolfo Lutz in 1908, it has been generally accepted that the disease is confined to South America. The few cases reported outside this region are of patients who lived for years in South American countries and probably contracted the “Lutz disease” there1–8.
openaire   +2 more sources

Digestion of killed Paracoccidioides brasiliensis by neutrophils

Mycopathologia, 1989
We previously described an in vitro assay showing that neutrophils (PMNs) from patients with paracoccidioidomycosis (PARA) have a specific digestive deficiency against suspensions of live Paracoccidioides brasiliensis. We now report that this defect is equally detectable against autoclaved, but not Amphotericin B-killed P. brasiliensis.
Mauricio Goihman-Yahr   +14 more
openaire   +2 more sources

Characteristics of Environmental Paracoccidioides brasiliensis Isolates

Mycopathologia, 2009
The ecological niche or exact habitat of the fungus Paracoccidioides brasiliensis is not known, and few isolates have been obtained from the environment. In this study, ten isolates were analyzed with respect to antigenic composition, serology, pathogenicity, and molecular aspects.
Patricia Fagundes, Costa   +4 more
openaire   +2 more sources

Effect of drying onParacoccidioides brasiliensis

Medical Mycology, 1971
The susceptibility to drying of Paracoccidioides brasiliensis growing on sterilized soils, was investigated using 2 strains with different sporulating capacities. Decreased fungal viability was noted during the 31 day experimental periods. The sporulating strain surpassed its initial viability at the fifth day when 75 days old culture was used, but not
I A, Conti-Diaz   +2 more
openaire   +2 more sources

Paracoccidioides brasiliensis, Paracoccidioidomycosis, and Antifungal Antibiotics

Current Drug Target -Infectious Disorders, 2005
Paracoccidioides brasiliensis is the causative agent of paracoccidioidomycosis (PCM), a human systemic, chronic and progressive mycosis. Preferred antifungals are sulfamethoxazol-trimethoprim, itraconazole, amphotericin B. Treatment is lengthy, the drugs may have undesirable side effects, and some are costly.
G, Visbal   +3 more
openaire   +2 more sources

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