Journal of Immunology Research, 2019 The glycoprotein gp43 is the major antigenic/diagnostic component of Paracoccidioides brasiliensis, one of the etiologic agents of paracoccidioidomycosis (PCM). Gp43 has protective roles in mice, but due to adhesive properties, this glycoprotein has also
Taiane Priscila Gardizani +6 more
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Paracoccidioides lutzii Plp43 is an active glucanase with partial antigenic identity with P. brasiliensis gp43. [PDF]
PLoS Neglected Tropical Diseases, 2014 Paracoccidioides brasiliensis and P. lutzii cause paracoccidioidomycosis (PCM). P. brasiliensis main diagnostic antigen is glycoprotein gp43, and its peptide sequence is 81% identical with a P. lutzii ortholog here called Plp43. P.
Natanael P Leitão +5 more
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Peptides derived from gp43, the most antigenic protein from Paracoccidioides brasiliensis, form amyloid fibrils in vitro: implications for vaccine development [PDF]
Scientific Reports, 2021 Fungal infection is an important health problem in Latin America, and in Brazil in particular. Paracoccidioides (mainly P. brasiliensis and P. lutzii) is responsible for paracoccidioidomycosis, a disease that affects mainly the lungs.
Thyago R. Cardim-Pires +2 more
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Molecular epidemiology of Paracoccidiodes spp. recovered from patients with paracoccidioidomycosis in a teaching hospital from Minas Gerais State of Brazil. [PDF]
PLoS Neglected Tropical Diseases, 2021 IntroductionParacoccidioidomycosis (PCM) is caused by several species of the Paracoccidioides genus which can be differentiated by interspecific genetic variations, morphology and geographic distribution.
Juliana Andrade-Silva +9 more
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Paracoccidioides brasiliensis-gp43 used as paracoccidioidin
Medical Mycology, 1996 A purified glycoprotein of 43 000 daltons from Paracoccidioides brasiliensis (gp43) was tested as paracoccidioidin in delayed-type hypersensitivity (DTH) tests in both experimental animals (guinea pig and mice) and patients with paracoccidioidomycosis ...
Z P Camargo, Z P Camargo
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Differences in reactivity of paracoccidioidomycosis sera with gp43 isoforms
Medical Mycology, 1997 The glycoprotein gp43 from Paracoccidioides brasiliensis is the main antigenic component in paracoccidioidomycosis (PCM) because it is recognized by 100% of PCM patients.
Z P Camargo +2 more
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Immunodiagnosis of paracoccidioidomycosis due to Paracoccidioides brasiliensis using a latex test: detection of specific antibody anti-gp43 and specific antigen gp43. [PDF]
PLoS Neglected Tropical Diseases, 2015 Paracoccidioidomycosis (PCM) is a life-threatening systemic disease and is a neglected public health problem in many endemic regions of Latin America.
Priscila Oliveira Dos Santos +5 more
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Two Cases of Lacaziosis in Bottlenose Dolphins (Tursiops truncatus) in Japan
Case Reports in Veterinary Medicine, 2013 Lacaziosis, formerly called lobomycosis, caused by Lacazia loboi, is a zoonotic mycosis found in humans and dolphins and is endemic in the countries on the Atlantic Ocean.
Keiichi Ueda +11 more
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Utility of the Bacteriophage RB69 Polymerase gp43 as a Surrogate Enzyme for Herpesvirus Orthologs
Viruses, 2013 Viral polymerases are important targets in drug discovery and development efforts. Most antiviral compounds that are currently approved for treatment of infection with members of the herpesviridae family were shown to inhibit the viral DNA polymerase ...
Nicholas Bennett
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In situ structures of the contractile nanomachine myophage Mu in both its extended and contracted states [PDF]
Journal of VirologyMyophage Mu is a representative of contractile nanomachines with a simple tail baseplate. It has the capacity to infect a range of intestinal bacteria and has extensive applications in genetic engineering research.
Junquan Zhou +7 more
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