Results 31 to 40 of about 1,086 (154)

N‐glycan signatures identified in tumor interstitial fluid and serum of breast cancer patients: association with tumor biology and clinical outcome

open access: yesMolecular Oncology, Volume 12, Issue 6, Page 972-990, June 2018., 2018
Using quantitative glycome profiling of breast tumor interstitial fluid and matched serum, we identified N‐glycan pattern that (a) segregates tumor and normal interstitual fluids, (b) correlates with the presence of immune cells within tumor, (c) can be predictive for overall survival outcome of patients with breast cancer, and (d) can be detected in ...
Thilde Terkelsen   +11 more
wiley   +1 more source

Diagnosis and Treatment of Paracoccidioidomycosis in the Maxillofacial Region: A Report of 5 Cases

open access: yesCase Reports in Otolaryngology, Volume 2018, Issue 1, 2018., 2018
Paracoccidioidomycosis is a fungal infection initially described in Brazil in 1908 by Adolfo Lutz. Manifestation of this disease depends on numerous factors, such as microorganism virulence, hormonal profile, genetic predisposition, nutrition, and immune system.
Antonio Dionízio De Albuquerque Neto   +6 more
wiley   +1 more source

Cancer Immunotherapy: Priming the Host Immune Response with Live Attenuated Salmonella enterica

open access: yesJournal of Immunology Research, Volume 2018, Issue 1, 2018., 2018
In recent years, cancer immunotherapy has undergone great advances because of our understanding of the immune response and the mechanisms through which tumor cells evade it. A century after the first immunotherapy attempt based on bacterial products described by William Coley, the use of live attenuated bacterial vectors has become a promising ...
Marco Antonio Hernández-Luna   +2 more
wiley   +1 more source

Polymorphism in the flanking regions of the PbGP43 gene from the human pathogen Paracoccidioides brasiliensis: search for protein binding sequences and poly(A) cleavage sites

open access: yesBMC Microbiology, 2009
Background Paracoccidioides brasiliensis is a thermo-dimorphic fungus that causes paracoccidiodomycosis (PCM). Glycoprotein gp43 is the fungal main diagnostic antigen, which can also protect against murine PCM and interact with extracellular matrix ...
Puccia Rosana   +2 more
doaj   +1 more source

Paracoccidioides Spp.: Virulence Factors and Immune‐Evasion Strategies

open access: yesMediators of Inflammation, Volume 2017, Issue 1, 2017., 2017
Paracoccidioides spp. are dimorphic fungal pathogens responsible for one of the most relevant systemic mycoses in Latin America, paracoccidioidomycosis (PCM). Their exact ecological niche remains unknown; however, they have been isolated from soil samples and armadillos (Dasypus novemcinctus), which have been proposed as animal reservoir for these ...
Emma Camacho   +2 more
wiley   +1 more source

Paracoccidioides cerebriformis Moore, 1935. MYCOLOGIC AND IMMUNOCHEMICAL STUDY

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 1997
The present study concern on mycologic and immunochemical data obtained from two samples of a fungus considered as belonging to the species Paracoccidioides cerebriformis described by Moore in 1935, and maintained since then on Sabouraud’s agar in the ...
Carlos da Silva LACAZ   +6 more
doaj   +1 more source

Antifungal Resistance, Metabolic Routes as Drug Targets, and New Antifungal Agents: An Overview about Endemic Dimorphic Fungi

open access: yesMediators of Inflammation, Volume 2017, Issue 1, 2017., 2017
Diseases caused by fungi can occur in healthy people, but immunocompromised patients are the major risk group for invasive fungal infections. Cases of fungal resistance and the difficulty of treatment make fungal infections a public health problem.
Juliana Alves Parente-Rocha   +7 more
wiley   +1 more source

Use of Recombinant gp43 Isoforms Expressed in Pichia pastoris for Diagnosis of Paracoccidioidomycosis

open access: yesClinical and Vaccine Immunology, 2008
ABSTRACT gp43 is the main diagnostic antigen for paracoccidioidomycosis (PCM). In vitro, gp43 expression in supernatant fluids of Paracoccidioides brasiliensis cultures can be unstable, and its regulation is poorly understood.
Carvalho, K. C. UNIFESP   +3 more
openaire   +3 more sources

cDNA cloning and sequence analysis of the Xenopus laevis egg envelope glycoprotein gp43 [PDF]

open access: yesDevelopment, Growth & Differentiation, 1997
The glycoproteins of the Xenopus laevis egg envelope function in fertilization and development. As the unfertilizable coelomic egg transits the pars recta region of the oviduct, it is converted to a fertilizable egg by limited proteolysis of the envelope glycoprotein gp43 to gp41.
J C, Yang, J L, Hedrick
openaire   +2 more sources

Cinnamic Acid Is Partially Involved in Propolis Immunomodulatory Action on Human Monocytes

open access: yesEvidence-Based Complementary and Alternative Medicine, Volume 2013, Issue 1, 2013., 2013
Propolis is a beehive product used in traditional medicine due to its biological properties. It shows a complex chemical composition including phenolics, such as cinnamic acid (Ci). The mechanisms of action of propolis have been the subject of research recently; however, the involvement of Ci on propolis activity was not investigated on immune cells ...
Bruno José Conti   +5 more
wiley   +1 more source

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