Results 31 to 40 of about 1,511 (158)

Cell-free antigens from precocious Paracoccidioides brasiliensis culture induce a typical delayed-type hypersensitivity reaction

open access: yesJournal of Venomous Animals and Toxins including Tropical Diseases, 2011
Cell-free antigens (CFAg) derived from Paracoccidioides brasiliensis have typically been used in immunodiffusion reactions for serodiagnosis or therapeutic follow-up of paracoccidioidomycosis patients.
Fecchio CJ   +5 more
doaj   +1 more source

N‐glycan signatures identified in tumor interstitial fluid and serum of breast cancer patients: association with tumor biology and clinical outcome

open access: yesMolecular Oncology, Volume 12, Issue 6, Page 972-990, June 2018., 2018
Using quantitative glycome profiling of breast tumor interstitial fluid and matched serum, we identified N‐glycan pattern that (a) segregates tumor and normal interstitual fluids, (b) correlates with the presence of immune cells within tumor, (c) can be predictive for overall survival outcome of patients with breast cancer, and (d) can be detected in ...
Thilde Terkelsen   +11 more
wiley   +1 more source

New developments of RNAi in Paracoccidioides brasiliensis: prospects for high-throughput, genome-wide, functional genomics. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2014
The Fungal Genome Initiative of the Broad Institute, in partnership with the Paracoccidioides research community, has recently sequenced the genome of representative isolates of this human-pathogen dimorphic fungus: Pb18 (S1), Pb03 (PS2) and Pb01.
Tercio Goes   +7 more
doaj   +1 more source

Diagnosis and Treatment of Paracoccidioidomycosis in the Maxillofacial Region: A Report of 5 Cases

open access: yesCase Reports in Otolaryngology, Volume 2018, Issue 1, 2018., 2018
Paracoccidioidomycosis is a fungal infection initially described in Brazil in 1908 by Adolfo Lutz. Manifestation of this disease depends on numerous factors, such as microorganism virulence, hormonal profile, genetic predisposition, nutrition, and immune system.
Antonio Dionízio De Albuquerque Neto   +6 more
wiley   +1 more source

Polymorphism in the flanking regions of the PbGP43 gene from the human pathogen Paracoccidioides brasiliensis: search for protein binding sequences and poly(A) cleavage sites

open access: yesBMC Microbiology, 2009
Background Paracoccidioides brasiliensis is a thermo-dimorphic fungus that causes paracoccidiodomycosis (PCM). Glycoprotein gp43 is the fungal main diagnostic antigen, which can also protect against murine PCM and interact with extracellular matrix ...
Puccia Rosana   +2 more
doaj   +1 more source

Cancer Immunotherapy: Priming the Host Immune Response with Live Attenuated Salmonella enterica

open access: yesJournal of Immunology Research, Volume 2018, Issue 1, 2018., 2018
In recent years, cancer immunotherapy has undergone great advances because of our understanding of the immune response and the mechanisms through which tumor cells evade it. A century after the first immunotherapy attempt based on bacterial products described by William Coley, the use of live attenuated bacterial vectors has become a promising ...
Marco Antonio Hernández-Luna   +2 more
wiley   +1 more source

Paracoccidioides cerebriformis Moore, 1935. MYCOLOGIC AND IMMUNOCHEMICAL STUDY

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 1997
The present study concern on mycologic and immunochemical data obtained from two samples of a fungus considered as belonging to the species Paracoccidioides cerebriformis described by Moore in 1935, and maintained since then on Sabouraud’s agar in the ...
Carlos da Silva LACAZ   +6 more
doaj   +1 more source

Paracoccidioides Spp.: Virulence Factors and Immune‐Evasion Strategies

open access: yesMediators of Inflammation, Volume 2017, Issue 1, 2017., 2017
Paracoccidioides spp. are dimorphic fungal pathogens responsible for one of the most relevant systemic mycoses in Latin America, paracoccidioidomycosis (PCM). Their exact ecological niche remains unknown; however, they have been isolated from soil samples and armadillos (Dasypus novemcinctus), which have been proposed as animal reservoir for these ...
Emma Camacho   +2 more
wiley   +1 more source

Antifungal Resistance, Metabolic Routes as Drug Targets, and New Antifungal Agents: An Overview about Endemic Dimorphic Fungi

open access: yesMediators of Inflammation, Volume 2017, Issue 1, 2017., 2017
Diseases caused by fungi can occur in healthy people, but immunocompromised patients are the major risk group for invasive fungal infections. Cases of fungal resistance and the difficulty of treatment make fungal infections a public health problem.
Juliana Alves Parente-Rocha   +7 more
wiley   +1 more source

Structural analysis of bacteriophage T4 DNA replication: a review in the Virology Journal series on bacteriophage T4 and its relatives

open access: yesVirology Journal, 2010
The bacteriophage T4 encodes 10 proteins, known collectively as the replisome, that are responsible for the replication of the phage genome. The replisomal proteins can be subdivided into three activities; the replicase, responsible for duplicating DNA ...
Boyer Ryan A   +4 more
doaj   +1 more source

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