Results 21 to 30 of about 1,511 (158)

Effect of molecular hydrogen treatment on Sepsis‐Associated encephalopathy in mice based on gut microbiota

CNS Neuroscience &Therapeutics, Volume 29, Issue 2, Page 633-645, February 2023., 2023
Molecular hydrogen treatment can significantly improve the gut microbiota and metabolites and reduce the inflammatory reaction and cognitive dysfunction after SAE. This study provides a basis for the pathogenesis and treatment of SAE. Abstract Introduction In our experiments, male wild‐type mice were randomly divided into four groups: the sham, SAE ...
Qingqing Han, Yuanyuan Bai, Chunjing Zhou, Beibei Dong, Yingning Li, Ning Luo, Hongguang Chen, Yonghao Yu   +7 more
wiley   +1 more source

Monocyte-Derived Dendritic Cells Can Revert In Vitro Antigen-Specific Cellular Anergy in Active Human Paracoccidioidomycosis

Journal of Fungi, 2021
We investigated the in vitro effects of two Paracoccidioides brasiliensis antigens on monocyte-derived dendritic cells (moDCs) from patients with paracoccidioidomycosis (PCM).
Paula Keiko Sato, Telma Miyuki Oshiro, Érika Cano Passos, Tatiana Giselle Rodrigues Miranda, Constância Lima Diogo, Claudia de Abreu Fonseca, Aya Sadahiro, Sandro Rogério de Almeida, Maria Aparecida Shikanai-Yasuda   +8 more
doaj   +1 more source

Gene expression of Paracoccidioides virulence factors after interaction with macrophages and fibroblasts [PDF]

Memorias do Instituto Oswaldo Cruz, 2021
BACKGROUND Paracoccidioidomycosis (PCM) is a systemic mycosis with high prevalence in Latin America that is caused by thermodimorphic fungal species of the Paracoccidioides genus.
Jaqueline Derissi Braz, Janaina de Cássia Orlandi Sardi, Nayla de Souza Pitangui, Aline Raquel Voltan, Ana Marisa Fusco Almeida, Maria José Soares Mendes-Giannini   +5 more
doaj   +1 more source

A Multiple Antigen Peptide Vaccine Containing CD4+ T Cell Epitopes Enhances Humoral Immunity against Trichinella spiralis Infection in Mice

Journal of Immunology Research, Volume 2020, Issue 1, 2020., 2020
Multiepitope peptide vaccine has some advantages over traditional recombinant protein vaccine due to its easy and fast production and possible inclusion of multiple protective epitopes of pathogens. However, it is usually poorly immunogenic and needs to conjugate to a large carrier protein.
Yuan Gu, Ximeng Sun, Jingjing Huang, Bin Zhan, Xinping Zhu, Yoshihiko Hoshino   +5 more
wiley   +1 more source

Kinetics of IFN-gamma, TNF-alpha, IL-10 and IL-4 production by mononuclear cells stimulated with gp43 peptides, in patients cured of paracoccidioidomycosis Cinética da produção de IFN-gama, TNF-alfa, IL-10 e IL-4 por células mononucleares, de pacientes curados de paracoccidoidomicose, estimuladas com peptídeos da gp43

Revista da Sociedade Brasileira de Medicina Tropical, 2007
We analyzed the kinetics of cytokine production by mononuclear cells from 17 patients who had been treated for paracoccidioidomycosis, using the stimulus of gp43 peptide groups (43kDa glycoprotein of Paracoccidioides brasiliensis) at 0.1 and 1µM, gp43 ...
Aya Sadahiro, Constancia Lima Diogo, Telma Miyuki Oshiro, Maria Aparecida Shikanai-Yasuda   +3 more
doaj   +1 more source

scFv from Antibody That Mimics gp43 Modulates the Cellular and Humoral Immune Responses during Experimental Paracoccidioidomycosis. [PDF]

PLoS ONE, 2015
Paracoccidioidomycosis (PCM), caused by Paracoccidioides species is a prevalent systemic and progressive mycosis that occurs in Latin America. It is caused by Paracoccidioides species. Immunization with dendritic cells transfected with a plasmid encoding
Grasielle Pereira Jannuzzi, Aldo Henrique F P Tavares, Gilberto Hideo Kaihami, José Roberto Fogaça de Almeida, Sandro Rogério de Almeida, Karen Spadari Ferreira   +5 more
doaj   +1 more source

Humoral immune response in experimental ddY mice Paracoccidioidomycosis/
Resposta imune humoral na paracoccidioidomicose experimental em camundongos ddY

Semina: Ciências Agrárias, 2007
Paracoccidioidomycosis (PCM) is a systemic mycosis, restrict to Latin America, with higher incidence in Brazil. ddY mice have been used as experimental PCM model, although there is no data regarding immune response.
Eiko Nakagawa Itano, Kazuko Nishimura, Makoto Miyaji, Yuzuru Mikami, Jun Uno, Ayako Sano, Berenice Tomoko Tatibana   +6 more
doaj   +1 more source

Cryptic species of Paracoccidioides brasiliensis: impact on paracoccidioidomycosis immunodiagnosis

Memorias do Instituto Oswaldo Cruz, 2013
We aimed to evaluate whether the occurrence of cryptic species of Paracoccidioides brasiliensis, S1, PS2, PS3 and Paracoccidioides lutzii, has implications in the immunodiagnosis of paracoccidioidomycosis (PCM).
Gabriel Capella Machado, Daniela Vanessa Moris, Thales Domingos Arantes, Luciane Regina Franciscone Silva, Raquel Cordeiro Theodoro, Rinaldo Pôncio Mendes, Adriana Pardini Vicentini, Eduardo Bagagli   +7 more
doaj   +1 more source

The Environment and Cyanophage Diversity: Insights From Environmental Sequencing of DNA Polymerase

Frontiers in Microbiology, 2019
Globally distributed and abundant cyanophages in the family Myoviridae have dsDNA genomes with variable gene content, including host-derived auxiliary metabolic genes (AMGs) that potentially can facilitate viral replication.
Jan F. Finke, Curtis A. Suttle, Curtis A. Suttle, Curtis A. Suttle, Curtis A. Suttle   +4 more
doaj   +1 more source

Comparison of clinico-epidemiological and radiological features in paracoccidioidomycosis patients regarding serological classification using antigens from Paracoccidioides brasiliensis complex and Paracoccidioides lutzii.

PLoS Neglected Tropical Diseases, 2020
Genotyping of the genus Paracoccidioides showed its diversity and geographical distribution. Four species constituting the Paracoccidioides brasiliensis complex and Paracoccidioides lutzii are etiological agents of paracoccidioidomycosis (PCM).
Edy F Pereira, Gregory Gegembauer, Marilene R Chang, Zoilo P de Camargo, Thiago F Nunes, Sergio M Ribeiro, Lídia R de Carvalho, Bianca M Maldonado, Rinaldo P Mendes, Anamaria M M Paniago   +9 more
doaj   +1 more source