Results 11 to 20 of about 1,511 (158)

Inhibition of PbGP43 expression may suggest that gp43 is a virulence factor in Paracoccidioides brasiliensis. [PDF]

open access: yesPLoS ONE, 2013
Glycoprotein gp43 is an immunodominant diagnostic antigen for paracoccidioidomycosis caused by Paracoccidioides brasiliensis. It is abundantly secreted in isolates such as Pb339. It is structurally related to beta-1,3-exoglucanases, however inactive. Its
Isaura Torres   +8 more
doaj   +3 more sources

Inquérito epidemiológico sobre a paracoccidioidomicose utilizando a gp43 em dois municípios do noroeste do Paraná, Brasil Paracoccidioidomycosis epidemiological survey using gp43, in two cities of northwestern region of Paraná, Brazil [PDF]

open access: yesRevista da Sociedade Brasileira de Medicina Tropical, 2005
Foi realizado um inquérito epidemiológico sobre paracoccidioidomicose com gp43, em 118 operários no Noroeste do Paraná. A positividade foi de 43%, o que aliado às condições ambientais favoráveis ao desenvolvimento do fungo reforçam que essa região seja ...
Nair Fornajeiro   +3 more
doaj   +2 more sources

GP43 from Paracoccidioides brasiliensis inhibits macrophage functions. An evasion mechanism of the fungus

open access: yesCellular Immunology, 2002
Macrophages constitute one of the primary cellular mechanisms that impairs parasite invasion of host tissues. The phagocytic and microbicidal properties of these cells can be modulated by specific membrane receptors involved in cell-microorganism ...
Ana Flavia Popi, José Daniel Lopes
exaly   +2 more sources

Variable gp43 Secretion by Paracoccidioides brasiliensis Clones Obtained by Two Different Culture Methods [PDF]

open access: yesJournal of Clinical Microbiology, 2005
The main objectives of this study were to obtain clones of Paracoccidioides brasiliensis by two methods (micromanipulation and plating assay) and to determine if the secretion of the 43-kDa glycoprotein (gp43) is dependent on the clonal culture.
Silvia Helena Marques-Da-Silva   +1 more
exaly   +2 more sources

Levels of specific antigen (gp43), specific antibodies, and antigen-antibody complexes in saliva and serum of paracoccidioidomycosis patients

open access: yesMedical Mycology, 2001
The present study analyses human immunoglobulin G (IgG) antibodies directed against the Paracoccidioides brasiliensis exoantigen, gp43, as well as the presence of gp43-IgG immune complexes (ICs) in 31 samples of saliva and serum from 19 patients with ...
José Daniel Lopes, E N Itano
exaly   +4 more sources

Interactions between TLR2, TLR4, and mannose receptors with gp43 fromParacoccidioides brasiliensisinduce cytokine production by human monocytes

open access: yesMedical Mycology, 2011
The glycoprotein gp43 is an immunodominant antigen secreted by Paracoccidioides brasiliensis, the agent of paracoccidioidomycosis. The present study evaluated whether gp43 can interact with toll-like (TLR2, TLR4) and mannose (MR) receptors on the surface
Maria Terezinha Peraçoli   +1 more
exaly   +2 more sources

Paracoccidioides Species Circulating in the Endemic Area of Rio de Janeiro, Brazil: Updates into Their Genetic Diversity [PDF]

open access: yesJournal of Fungi
Paracoccidiodomycosis (PCM) is the most important systemic mycosis in Brazil, and is usually associated with rural work. PCM is caused by inhalation of infective propagules of thermodimorphic fungi from the genus Paracoccidioides.
Beatriz da Silva Motta   +6 more
doaj   +2 more sources

DNA-based vaccination against murine paracoccidioidomycosis using the gp43 gene from Paracoccidioides brasiliensis

open access: yesVaccine, 2000
Gp43, the major 43-kDa antigenic glycoprotein of Paracoccidioides brasiliensis, or its 15-amino acid inner peptide (P10), induces a T-CD4(+), Th1 cellular immune response which protects BALB/c mice from intratracheal infection by virulent yeast forms. We
Aguinaldo Roberto Pinto   +2 more
exaly   +2 more sources

Peptides from Paracoccidioides brasiliensis GP43 inhibit macrophage functions and inflammatory response

open access: yesMicrobes and Infection, 2009
Paracoccidioidomycosis (PCM) is a systemic granulomatous disease caused by Paracoccidioides brasiliensis (Pb), a thermal dimorphic fungus. Its major antigen is a 43-kDa glycoprotein.
Maricato Jt   +2 more
exaly   +2 more sources

The story of Paracoccidiodes gp43 [PDF]

open access: yesBrazilian Journal of Microbiology, 2023
Rosana Puccia
exaly   +2 more sources

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