Foi realizado um inquérito epidemiológico sobre paracoccidioidomicose com gp43, em 118 operários no Noroeste do Paraná. A positividade foi de 43%, o que aliado às condições ambientais favoráveis ao desenvolvimento do fungo reforçam que essa região seja ...
Nair Fornajeiro +3 more
doaj +1 more source
New developments of RNAi in Paracoccidioides brasiliensis: prospects for high-throughput, genome-wide, functional genomics. [PDF]
The Fungal Genome Initiative of the Broad Institute, in partnership with the Paracoccidioides research community, has recently sequenced the genome of representative isolates of this human-pathogen dimorphic fungus: Pb18 (S1), Pb03 (PS2) and Pb01.
Tercio Goes +7 more
doaj +1 more source
Cancer Immunotherapy: Priming the Host Immune Response with Live Attenuated Salmonella enterica
In recent years, cancer immunotherapy has undergone great advances because of our understanding of the immune response and the mechanisms through which tumor cells evade it. A century after the first immunotherapy attempt based on bacterial products described by William Coley, the use of live attenuated bacterial vectors has become a promising ...
Marco Antonio Hernández-Luna +2 more
wiley +1 more source
Background Paracoccidioides brasiliensis is a thermo-dimorphic fungus that causes paracoccidiodomycosis (PCM). Glycoprotein gp43 is the fungal main diagnostic antigen, which can also protect against murine PCM and interact with extracellular matrix ...
Puccia Rosana +2 more
doaj +1 more source
DNA vaccine encoding peptide P10 against experimental paracoccidioidomycosis induces long-term protection in presence of regulatory T cells [PDF]
Paracoccidioidomycosis is a granulomatous systemic mycosis endemic in Brazil and other Latin America countries. A DNA vaccine encoding the inununoprotective peptide 10 (P10) significantly reduced the fungal burden in mice when given prior to or after ...
Amorim, Juliana de +6 more
core +2 more sources
Paracoccidioides Spp.: Virulence Factors and Immune‐Evasion Strategies
Paracoccidioides spp. are dimorphic fungal pathogens responsible for one of the most relevant systemic mycoses in Latin America, paracoccidioidomycosis (PCM). Their exact ecological niche remains unknown; however, they have been isolated from soil samples and armadillos (Dasypus novemcinctus), which have been proposed as animal reservoir for these ...
Emma Camacho +2 more
wiley +1 more source
Paracoccidioides cerebriformis Moore, 1935. MYCOLOGIC AND IMMUNOCHEMICAL STUDY
The present study concern on mycologic and immunochemical data obtained from two samples of a fungus considered as belonging to the species Paracoccidioides cerebriformis described by Moore in 1935, and maintained since then on Sabouraud’s agar in the ...
Carlos da Silva LACAZ +6 more
doaj +1 more source
Genome size and ploidy of Paracoccidioides brasiliensis reveals a haploid DNA content: Flow cytometry and GP43 sequence analysis [PDF]
The aim of this study was to evaluate genome size and ploidy of the dimorphic pathogenic fungus Paracoccidioides brasiliensis. The cell cycle analysis of 10 P. brasiliensis isolates by flow cytometry (FCM) revealed a genome size ranging from 26.3+/-0.1Mb
Almeida, A. J. +9 more
core +1 more source
Diseases caused by fungi can occur in healthy people, but immunocompromised patients are the major risk group for invasive fungal infections. Cases of fungal resistance and the difficulty of treatment make fungal infections a public health problem.
Juliana Alves Parente-Rocha +7 more
wiley +1 more source
Comparison of the human immune responses to recombinant proteins representing three distinct surface proteins of Plasmodium vivax merozoites [PDF]
Universidade Federal de São Paulo (UNIFESP), Escola Paulista de Medicina (EPM) Departamento de Microbiologia, Imunologia e ParasitologiaUniversidade Federal do Pará Departamento de PatologiaCenters for Disease Control and Prevention Division of Parasitic
Barnwell, John W. +7 more
core +3 more sources

