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Cinnamic Acid Is Partially Involved in Propolis Immunomodulatory Action on Human Monocytes
Propolis is a beehive product used in traditional medicine due to its biological properties. It shows a complex chemical composition including phenolics, such as cinnamic acid (Ci). The mechanisms of action of propolis have been the subject of research recently; however, the involvement of Ci on propolis activity was not investigated on immune cells ...
Bruno José Conti +5 more
wiley +1 more source
PbGP43 aRNA mutants showed reduced levels of secreted gp43.
(A) Silver stained poliacrylamide gel of culture supernatant (day 12) from PbWt and mutant PbGP43 aRNA1 at the indicated volumes. P27 low-expression strain (PbP27 aRNA) was used as Pb339 recombinant control.
Jose F. Muñoz (433074) +8 more
core +1 more source
Paracoccidioidomycosis is the most important systemic mycosis in Latin America. The main entrance of the fungus is the airway. It primarily occurs in the lung, but in its disseminated form may affect any organ. The liver is one of the organs afflicted by
Elaine Sciuniti Benites Mansano +7 more
doaj +1 more source
Data are n(%).Detection of anti-gp43 antibody and gp43 antigen in bronchoalveolar lavage (BAL) fluid from patients with or without paracoccidioidomycosis (PCM).
Priscila Oliveira dos Santos (697722) +5 more
core +1 more source
Paracoccidioidomycosis (PCM) is a systemic granulomatous fungal infection caused by thermally dimorphic fungi of the genus Paracoccidioides. Endemic in Latin America, PCM presents with high incidence in Brazil, Colombia, and Venezuela, especially among ...
Débora de Fátima Almeida Donanzam +12 more
doaj +1 more source
Instability of repetitive sequences originates from strand misalignment during repair or replicative DNA synthesis. To investigate the activity of reconstituted T4 replisomes across trinucleotide repeats (TNRs) during leading strand DNA synthesis, we developed a method to build replication miniforks containing a TNR unit of defined sequence and length.
Emmanuelle Delagoutte +2 more
wiley +1 more source
Saccharomyces cerevisiae expressing Gp43 protects mice against Paracoccidioides brasiliensis infection. [PDF]
The dimorphic fungus Paracoccidioides brasiliensis is the etiological agent of paracoccidioidomycosis (PCM). It is believed that approximately 10 million people are infected with the fungus and approximately 2% will eventually develop the disease. Unlike
Mariana Aprigio Assis-Marques +5 more
doaj +1 more source
Data are n(%). PCM, paracoccidioidomycosis; NHS, normal healthy subjects.Detection of anti-gp43 antibody and gp43 antigen in sera from patients with or without fungal disease.
Priscila Oliveira dos Santos (697722) +5 more
core +1 more source
Flagellins as Vaccine Adjuvants and Cancer Immunotherapy: Recent Advances and Future Prospects
The figure depicts the role of flagellin in immune cells. Flagellin interacts with TLR5, resulting in the formation of homodimers and the recruitment of MyD88, which activates the IκB and MAPK signalling pathways. This results in the activation of NF‐κB and AP‐1, producing TNF‐α, IL‐6, IL‐8, and IL‐12.
Asma Talukder +4 more
wiley +1 more source
Paracoccidioidomycosis is a systemic and endemic mycosis, restricted to tropical and subtropical areas of Latin America. The infection is caused by the thermal dimorphic fungus Paracoccidioides brasiliensis and Paracoccidioides lutzii.
Marcela Gaviria +4 more
doaj +1 more source

