Results 41 to 50 of about 1,086 (154)

Structural analysis of bacteriophage T4 DNA replication: a review in the Virology Journal series on bacteriophage T4 and its relatives

Virology Journal, 2010
The bacteriophage T4 encodes 10 proteins, known collectively as the replisome, that are responsible for the replication of the phage genome. The replisomal proteins can be subdivided into three activities; the replicase, responsible for duplicating DNA ...
Boyer Ryan A, Devos Juliette M, Hinerman Jennifer M, Mueser Timothy C, Williams Kandace J   +4 more
doaj   +1 more source

Identification of a bifunctional primase–polymerase domain of corynephage BFK20 replication protein gp43

Virus Research, 2012
Replication protein gp43 is a gene product of orf43, from the genome of corynephage BFK20 and carries two different domains. The C-terminal part of gp43 is similar to F4-type helicases and the N-terminal part resembles the rare primase-polymerase (prim-pol) domain.
Nora, Halgasova, Irena, Mesarosova, Gabriela, Bukovska   +2 more
openaire   +2 more sources

Expression of glycoprotein gp43 in stage-specific forms and during dimorphic differentiation ofParacoccidioides brasiliensis [PDF]

Medical Mycology, 1997
Expression of the 43 kDa glycoprotein (gp43) was analysed in several Paracoccidioides brasiliensis isolates. Using one- and two-dimensional analysis of crude cellular extracts, it was shown that protein expression in yeast and mycelium was dependent on the isolate analysed. In two strains, in both yeast and mycelium cells.
R, Mattar-Filho, M O, Azevedo, M, Pereira, R S, Jesuino, S M, Salem-Izacc, W A, Brito, J L, Gesztesi, R B, Soares, M S, Felipe, C M, Soares   +9 more
openaire   +2 more sources

Variable gp43 Secretion by Paracoccidioides brasiliensis Clones Obtained by Two Different Culture Methods [PDF]

Journal of Clinical Microbiology, 2005
ABSTRACT The main objectives of this study were to obtain clones of Paracoccidioides brasiliensis by two methods (micromanipulation and plating assay) and to determine if the secretion of the 43-kDa glycoprotein (gp43) is dependent on the clonal culture.
Berzaghi, Rodrigo UNIFESP, Silva, Silvia Helena M da UNIFESP, Camargo, Zoilo Pires de UNIFESP   +2 more
openaire   +3 more sources

5′CAG and 5′CTG Repeats Create Differential Impediment to the Progression of a Minimal Reconstituted T4 Replisome Depending on the Concentration of dNTPs

Molecular Biology International, Volume 2011, Issue 1, 2011., 2011
Instability of repetitive sequences originates from strand misalignment during repair or replicative DNA synthesis. To investigate the activity of reconstituted T4 replisomes across trinucleotide repeats (TNRs) during leading strand DNA synthesis, we developed a method to build replication miniforks containing a TNR unit of defined sequence and length.
Emmanuelle Delagoutte, Giuseppe Baldacci, Giuseppina Giglia-Mari   +2 more
wiley   +1 more source

Correlation between histopathological and FT-Raman spectroscopy analysis of the liver of Swiss mice infected with Paracoccidioides brasiliensis.

PLoS ONE, 2014
Paracoccidioidomycosis is the most important systemic mycosis in Latin America. The main entrance of the fungus is the airway. It primarily occurs in the lung, but in its disseminated form may affect any organ. The liver is one of the organs afflicted by
Elaine Sciuniti Benites Mansano, Gutierrez Rodrigues de Morais, Edilaine Martins Moratto, Francielle Sato, Antonio Medina Neto, Terezinha Ines Estivalet Svidzinski, Mauro Luciano Baesso, Luzmarina Hernandes   +7 more
doaj   +1 more source

Exoantigens of Paracoccidioides spp. Promote Proliferation and Modulation of Human and Mouse Pulmonary Fibroblasts

Frontiers in Cellular and Infection Microbiology, 2020
Paracoccidioidomycosis (PCM) is a systemic granulomatous fungal infection caused by thermally dimorphic fungi of the genus Paracoccidioides. Endemic in Latin America, PCM presents with high incidence in Brazil, Colombia, and Venezuela, especially among ...
Débora de Fátima Almeida Donanzam, Débora de Fátima Almeida Donanzam, Tatiani Ayako Goto Donato, Karoline Haghata dos Reis, Adriely Primo da Silva, Angela Carolina Finato, Amanda Ribeiro dos Santos, Amanda Ribeiro dos Santos, Ricardo Souza Cavalcante, Rinaldo Poncio Mendes, Rinaldo Poncio Mendes, James Venturini, James Venturini   +12 more
doaj   +1 more source

Genetic evidence of a hybrid swarm between Alpine ibex (Capra ibex) and domestic goat (C. hircus)

Evolutionary Applications, Volume 17, Issue 8, August 2024.
Abstract Improving the understanding of the causes and effects of anthropogenic hybridization is fundamental to ensure species conservation, particularly in the case of hybridization between wild species and their domestic relatives. Knowledge is missing for many species also because of a lack of appropriate tools for hybrid identification.
Alice Brambilla, Noel Zehnder, Bruno Bassano, Luca Rossi, Christine Grossen   +4 more
wiley   +1 more source

Validation and clinical application of a nested PCR for paracoccidioidomycosis diagnosis in clinical samples from Colombian patients

Brazilian Journal of Infectious Diseases, 2015
Paracoccidioidomycosis is a systemic and endemic mycosis, restricted to tropical and subtropical areas of Latin America. The infection is caused by the thermal dimorphic fungus Paracoccidioides brasiliensis and Paracoccidioides lutzii.
Marcela Gaviria, Vanessa Rivera, Cesar Muñoz-Cadavid, Luz Elena Cano, Tonny Williams Naranjo   +4 more
doaj   +1 more source

Central nervous system paracoccidioidomycosis: analysis of 13 cases with immunofluorescence research of gp43 antigen [PDF]

Arquivos de Neuro-Psiquiatria, 2001
Paracoccidioidomycosis (PCM) is a systemic granulomatous disease caused by Paracoccidioides brasiliensis, prevalent in Latin America, particularly in Brazil. Central nervous system (CNS) involvement occur in about 10% of cases, although such cases are uncommon in the literature […] Central nervous system paracoccidioidomycosis: analysis of 13 cases ...
Walter J. Fagundes-Pereyra
doaj   +3 more sources