An archaeal family-B DNA polymerase variant able to replicate past DNA damage: occurrence of replicative and translesion synthesis polymerases within the B family [PDF]
A mutant of the high fidelity family-B DNA polymerase from the archaeon Thermococcus gorgonarius (Tgo-Pol), able to replicate past DNA lesions, is described.
Aidan J. Doherty +68 more
core +1 more source
Variable gp43 Secretion by Paracoccidioides brasiliensis Clones Obtained by Two Different Culture Methods [PDF]
ABSTRACT The main objectives of this study were to obtain clones of Paracoccidioides brasiliensis by two methods (micromanipulation and plating assay) and to determine if the secretion of the 43-kDa glycoprotein (gp43) is dependent on the clonal culture.
Berzaghi, Rodrigo UNIFESP +2 more
openaire +3 more sources
Paracoccidioidomycosis: advances and unmet needs 100 years after its initial description by Lutz [PDF]
Universidade Federal de São Paulo (UNIFESP) Departamento de MedicinaUNIFESP, Depto.
Colombo, Arnaldo Lopes
core +2 more sources
Genetic evidence of a hybrid swarm between Alpine ibex (Capra ibex) and domestic goat (C. hircus)
Abstract Improving the understanding of the causes and effects of anthropogenic hybridization is fundamental to ensure species conservation, particularly in the case of hybridization between wild species and their domestic relatives. Knowledge is missing for many species also because of a lack of appropriate tools for hybrid identification.
Alice Brambilla +4 more
wiley +1 more source
New advances in the development of a vaccine against paracoccidiodomycosis.
Paracoccidioidomycosis is an endemic Latin American mycosis caused by Paracoccidioides brasiliensis and also by the recently described P. lutzii. The systemic mycosis is the 10th leading cause of death due to infectious diseases in Brazil. As published,
Luiz R R. Travassos +1 more
doaj +1 more source
Central nervous system paracoccidioidomycosis: analysis of 13 cases with immunofluorescence research of gp43 antigen [PDF]
Paracoccidioidomycosis (PCM) is a systemic granulomatous disease caused by Paracoccidioides brasiliensis, prevalent in Latin America, particularly in Brazil. Central nervous system (CNS) involvement occur in about 10% of cases, although such cases are uncommon in the literature […] Central nervous system paracoccidioidomycosis: analysis of 13 cases ...
Walter J. Fagundes-Pereyra
doaj +3 more sources
Genomes of marine cyanopodoviruses reveal multiple origins of diversity [PDF]
The marine cyanobacteria Prochlorococcus and Synechococcus are highly abundant in the global oceans, as are the cyanophage with which they co-evolve. While genomic analyses have been relatively extensive for cyanomyoviruses, only three cyanopodoviruses ...
Angly +100 more
core +1 more source
Artificial Processive Catalytic Systems
A processive catalyst undergoes several rounds of catalysis before it is released from the substrate. The drawing shows possible ways (A–D) in which a synthetic catalyst can interact with the substrate to achieve processivity. Abstract Processive catalysts remain attached to a substrate and perform multiple rounds of catalysis.
Roeland J. M. Nolte +1 more
wiley +1 more source
Atypical Serological Response Marked by a Lack of Detectable Anti-gp43 Antibodies in a Patient with Disseminated Paracoccidioidomycosis [PDF]
ABSTRACT Serological tests are frequently used to diagnosis paracoccidioidomycosis. A glycoprotein of 43 kDa is considered to be the main diagnostic antigen, being recognized by virtually all patients' sera. A case of atypical serological response, consisting of a lack of detectable anti-gp43 antibodies, in a patient with disseminated ...
Mônica S M, Vidal +7 more
openaire +2 more sources
Paracoccidioidomycosis is a systemic and endemic mycosis, restricted to tropical and subtropical areas of Latin America. The infection is caused by the thermal dimorphic fungus Paracoccidioides brasiliensis and Paracoccidioides lutzii.
Marcela Gaviria +4 more
doaj +1 more source

