Results 201 to 210 of about 30,716 (258)
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Isoenzyme profile ofParacoccidioides brasiliensis
Medical Mycology, 1995Isoenzyme profiles of 10 strains of Paracoccidioides brasiliensis from different origins (nine strains from patients with different clinical forms of paracoccidioidomycosis and one from the faeces of a penguin) were determined by polyacrylamide gel electrophoresis using 37 different enzymes.
T I, Svidzinsky, Z P, Camargo
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Production of proteinase and phospholipase by Paracoccidioides brasiliensis
Mycopathologia, 1999We have investigated the production of proteinase and phospholipase by 20 different isolates of Paracoccidioides brasiliensis. Isolates were grown in Bacto-peptone, Dextrose, pH 5.5, agar slants, at 27 degrees C for 30 days, and cultures were transferred onto Petri dishes containing basis medium and bovine serum albumin fraction V and sterile egg yolk ...
C M, de Assis, W, Gambale, C R, Paula
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Digestion of killed Paracoccidioides brasiliensis by neutrophils
Mycopathologia, 1989We previously described an in vitro assay showing that neutrophils (PMNs) from patients with paracoccidioidomycosis (PARA) have a specific digestive deficiency against suspensions of live Paracoccidioides brasiliensis. We now report that this defect is equally detectable against autoclaved, but not Amphotericin B-killed P. brasiliensis.
Mauricio Goihman-Yahr +14 more
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Blastomyces (Paracoccidioides) brasiliensis in Africa
Nature, 1964SINCE the discovery of “South American Blastomycosis” by Adolfo Lutz in 1908, it has been generally accepted that the disease is confined to South America. The few cases reported outside this region are of patients who lived for years in South American countries and probably contracted the “Lutz disease” there1–8.
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Cytosolic Neutral Proteinases of Paracoccidioides brasiliensis
Current Microbiology, 1998Cytosolic proteinases were assayed in both morphological phases of Paracoccidioides brasiliensis. Preparations from the mycelial phase were more active in vitro than those from the yeast cells. Optimal proteinase activities for both phases occurred at pH's between 6.0 and 9.0, and at 45 degrees C.
G, San-Blas +4 more
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Paracoccidioides brasiliensis, Paracoccidioidomycosis, and Antifungal Antibiotics
Current Drug Target -Infectious Disorders, 2005Paracoccidioides brasiliensis is the causative agent of paracoccidioidomycosis (PCM), a human systemic, chronic and progressive mycosis. Preferred antifungals are sulfamethoxazol-trimethoprim, itraconazole, amphotericin B. Treatment is lengthy, the drugs may have undesirable side effects, and some are costly.
G, Visbal +3 more
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Characteristics of Environmental Paracoccidioides brasiliensis Isolates
Mycopathologia, 2009The ecological niche or exact habitat of the fungus Paracoccidioides brasiliensis is not known, and few isolates have been obtained from the environment. In this study, ten isolates were analyzed with respect to antigenic composition, serology, pathogenicity, and molecular aspects.
Patricia Fagundes, Costa +4 more
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Morphogenesis in Paracoccidioides brasiliensis
2011Paracoccidioidomycosis (PCM) is a deep systemic mycosis originally described in 1908 caused by the ascomycete Paracoccidioides brasiliensis, a thermodimorphic fungal pathogen. The disease is autochthonous to Latin America and areas of higher incidence occur in countries such as Brazil, Argentina, Colombia, and Venezuela.
Iran Malavazi, Gustavo Henrique Goldman
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Future Microbiology, 2019
Aim: A structural model of chorismate synthase (CS) from the pathogenic fungus Candida albicans was used for virtual screening simulations. Methods: Docking, molecular dynamics, cell growth inhibition and protein binding assays were used for search and ...
Paulo S. A. Bueno +5 more
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Aim: A structural model of chorismate synthase (CS) from the pathogenic fungus Candida albicans was used for virtual screening simulations. Methods: Docking, molecular dynamics, cell growth inhibition and protein binding assays were used for search and ...
Paulo S. A. Bueno +5 more
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Effect of drying onParacoccidioides brasiliensis
Medical Mycology, 1971The susceptibility to drying of Paracoccidioides brasiliensis growing on sterilized soils, was investigated using 2 strains with different sporulating capacities. Decreased fungal viability was noted during the 31 day experimental periods. The sporulating strain surpassed its initial viability at the fifth day when 75 days old culture was used, but not
I A, Conti-Diaz +2 more
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