Results 81 to 90 of about 4,608,970 (389)
Contro l’attendismo bibliotecario: quadri di un’esposizione
AIB Studi, 2020 Il periodo dell’epidemia da Covid-19 ha fatto emergere in modo irrevocabile la necessità di un generale ripensamento dei comportamenti, dei valori prioritari, della socialità, della distribuzione delle risorse.
Luca Ferrieri
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Considerations for the Mobile Web. Paradigm Shift [PDF]
Informatică economică, 2017 Google’s response to that trend and the what such changes entail further for website developers are issues around which this paper is built. In the first part of this paper we made an analysis of the literature in order to clarify certain terminology and
Romeo MARGEA, Camelia MARGEA
doaj +1 more source
, 2020 This study analyzed the current situation of education in the context of the pandemic caused by COVID-19. The worldwide health emergency situation has caused the confinement of people and with it, the closure of centers and the transfer of face-to-face ...
Luis Espino-Díaz +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Transitioning from change detection to monitoring with remote sensing: A paradigm shift
, 2020 The use of time series analysis with moderate resolution satellite imagery is increasingly common, particularly since the advent of freely available Landsat data. Dense time series analysis is providing new information on the timing of landscape changes,
C. Woodcock +3 more
semanticscholar +1 more source
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Accelerating Therapeutics for Opportunities in Medicine: A Paradigm Shift in Drug Discovery
Frontiers in Pharmacology, 2020 Conventional drug discovery is long and costly, and suffers from high attrition rates, often leaving patients with limited or expensive treatment options.
Izumi V. Hinkson +2 more
semanticscholar +1 more source