Results 31 to 40 of about 2,989,160 (264)

Natural and cryptic peptides dominate the immunopeptidome of atypical teratoid rhabdoid tumors

open access: yesJournal for ImmunoTherapy of Cancer, 2021
Background Atypical teratoid/rhabdoid tumors (AT/RT) are highly aggressive CNS tumors of infancy and early childhood. Hallmark is the surprisingly simple genome with inactivating mutations or deletions in the SMARCB1 gene as the oncogenic driver ...
Martin Ebinger   +20 more
doaj   +1 more source

Bone and Soft Tissue Neoplasms in Infants Versus Older Children: A Report From the Cancer in Young People in Canada Program

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Infant bone and soft tissue neoplasms present distinct clinical challenges and lack large‐scale data to inform treatment decisions. This study aims to characterize bone and soft tissue neoplasms in infants in Canada and to compare their outcomes with those of older pediatric patients.
Samuel Sassine   +21 more
wiley   +1 more source

Morfonologia tematu rumuńskich derywatów paradygmatycznych. Alternacje i ich funkcje

open access: yesSlavia Meridionalis, 2018
Stem morphophonology in Romanian paradigmatic derivatives: alternations and their functions Paradigmatic derivation is one of the basic word formation processes in Romanian. The aim of this paper is a characterization of its formal exponents. The work
Tomasz Cychnerski
doaj   +1 more source

Turing instability analysis of a singular cross-diffusion problem

open access: yesElectronic Journal of Differential Equations, 2021
The population model by Busenberg and Travis is a paradigmatic model in ecology and tumor modeling because its ability to capture interesting phenomena such as segregation of populations. Its singular mathematical structure enforces the consideration of
Gonzalo Galiano   +1 more
doaj   +1 more source

Paradigmatic relations in the class of pronouns [PDF]

open access: yesДоклады Башкирского университета, 2021
R. A. Gazizov, R. Z. Muryasov
openaire   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

ECONOMICS AS CULTURE: SYNERGY OF ADVANCED DEVELOPMENT

open access: yesBaltic Journal of Economic Studies, 2021
Economic systems are viewed as sociocultural phenomena of an ontological order. The hypothesis of a trialectic-dual and attractional-level nature of the implementation of cultural-paternalistic projects in the institutional sphere of economic relations ...
Petro Kutsyk   +2 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Urmson J. O. Polymorphous concepts / trans. from Engl. by A. V. Nekhaev, I. N. Nekhaeva

open access: yesОмский научный вестник: Серия "Общество. История. Современность"
The article attempts to clarify the criteria for Ryle’s class of polymorphous concepts. Ryle calls paradigmatic examples of the class such concepts as working and thinking.
A. V. Nekhaev, I. N. Nekhaeva
doaj   +1 more source

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