Results 41 to 50 of about 2,989,160 (264)

Categories We Do Not Know We Live By

open access: yesJournal of Social Ontology, 2022
I argue that a central claim of Ásta’s conferralist framework – that it can account for all social properties of individuals – is false, by drawing attention to (opaque) class.
Åsa Burman
doaj  

Illustration of the hypothetical semantic network created by syntagmatic and paradigmatic relations.

open access: yes, 2015
Solid lines denote paradigmatic relations, while dashed lines denote syntagmatic relations. The color of a node indicates the word class of the corresponding word (green = noun, yellow = adjective, red = verb).
Akira Utsumi (524739)
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

(Almost) everything is a Dicke model - Mapping non-superradiant correlated light-matter systems to the exactly solvable Dicke model

open access: yesSciPost Physics Core
We investigate classes of interacting quantum spin systems in a single-mode cavity with a Dicke coupling, as a paradigmatic example of strongly correlated light-matter systems.
Andreas Schellenberger, Kai Phillip Schmidt
doaj   +1 more source

La « médiocrité dorée » dans l’œuvre austenienne : des « middle ranks » à l’émergence de la « middle class » ?

open access: yesXVII-XVIII, 2015
Jane Austen’s œuvre was composed at a time when the paradigmatic shift from the concept of “rank” to that of “class” was well under way. Her novels thus subtly dramatise the social transformations inherent in the advent of a new economic and financial ...
Marie-Laure Massei-Chamayou
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Morfo-metafonia e vocalismo marginale nei dialetti salentini settentrionali

open access: yesAtti del Sodalizio Glottologico Milanese
The northern Salentino vowel system, provided with five stressed vowels, is nowadays conceived as an original Sicilian system, later influenced by the Neapolitan one. Indeed, each of the two mid vowels shows two different metaphonic outcomes (/ɛ‒MET/ ~ /
Alessandro De Angelis
doaj   +1 more source

MECHANISMS AND REGULARITIES OF DEVELOPMENT OF INTELLIGENCE OF THE MANAGEMENT CLASS IN RUSSIA

open access: yesSovremennye Issledovaniâ Socialʹnyh Problem, 2015
The article is devoted to identification and analysis of mechanisms and regularities of development of intelligence of the political elite of our country and assessment of condition of its intellectual development.For solution of the tasks in hand the ...
Svetlana Ryabkova
doaj   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

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