Results 41 to 50 of about 6,185 (233)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Categories We Do Not Know We Live By
Journal of Social Ontology, 2022 I argue that a central claim of Ásta’s conferralist framework – that it can account for all social properties of individuals – is false, by drawing attention to (opaque) class.
Åsa Burman
doaj
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
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Urmson J. O. Polymorphous concepts / trans. from Engl. by A. V. Nekhaev, I. N. Nekhaeva
Омский научный вестник: Серия "Общество. История. Современность"The article attempts to clarify the criteria for Ryle’s class of polymorphous concepts. Ryle calls paradigmatic examples of the class such concepts as working and thinking.
A. V. Nekhaev, I. N. Nekhaeva
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XVII-XVIII, 2015 Jane Austen’s œuvre was composed at a time when the paradigmatic shift from the concept of “rank” to that of “class” was well under way. Her novels thus subtly dramatise the social transformations inherent in the advent of a new economic and financial ...
Marie-Laure Massei-Chamayou
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
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SciPost Physics CoreWe investigate classes of interacting quantum spin systems in a single-mode cavity with a Dicke coupling, as a paradigmatic example of strongly correlated light-matter systems.
Andreas Schellenberger, Kai Phillip Schmidt
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Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
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Morfo-metafonia e vocalismo marginale nei dialetti salentini settentrionali
Atti del Sodalizio Glottologico MilaneseThe northern Salentino vowel system, provided with five stressed vowels, is nowadays conceived as an original Sicilian system, later influenced by the Neapolitan one. Indeed, each of the two mid vowels shows two different metaphonic outcomes (/ɛ‒MET/ ~ /
Alessandro De Angelis
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