Results 231 to 240 of about 956,237 (293)

Amelioration of Post‐Stroke Edema and Microcirculatory Dysfunction via Targeted AQP4 Inhibition While Preserving the Glymphatic System

Advanced Science, EarlyView.
Compared to untargeted therapy, the targeted nanocarrier, Angiopep‐2‐conjugated Lipid Nanoparticle (A‐LNP) loaded with TGN‐020 (TGN), selectively accumulated in stroke‐injured regions. It suppressed local aquaporin‐4 (AQP4) overexpression, thereby alleviating cerebral edema and hypoperfusion while preserving global glymphatic clearance.
Lei Jin, Zeyu Yang, Boyang Wei, Yu Wu, Longxiang Li, Jiaming Zhou, Xin Zhang, Fa Jin, Shixing Su, Yanchao Liu, Ran Li, Shenquan Guo, Xingwu Liu, Yu Cai, Hong Liu, Min Chen, Wenchao Liu, Chuanzhi Duan, Xifeng Li   +18 more
wiley   +1 more source

Association of Race, Ethnicity, and Area Deprivation With the Prevalence of Atrial Fibrillation in a Large US Population. [PDF]

Circ Arrhythm Electrophysiol
Alonso A, Najarro G, Shah AJ, Li L, Lewis TT.   +4 more
europepmc   +1 more source

The hybrid layer paradox: Rethinking the foundations of adhesive dentistry. [PDF]

J Conserv Dent Endod
Singh S, Chandrashekhar P.
europepmc   +1 more source

Measuring What Matters: The Pseudo-Productivity Paradox in Health Care. [PDF]

Chest
Matson SM.
europepmc   +1 more source

Development of Uncertainty Sensitivity: Early Competence or Protracted Development? [PDF]

Dev Sci
Wan Q, Sloutsky VM.
europepmc   +1 more source

Reevaluating the obesity paradox across diverse disease outcomes: A Mendelian randomization study. [PDF]

Medicine (Baltimore)
Cong P, Li Y.
europepmc   +1 more source