Results 281 to 290 of about 1,405,451 (393)

The Paradox of an Empire by Treaty

open access: green, 2014
Belmessous, S ; https://orcid.org/0000-0001-9392-8921
openalex   +2 more sources

Nanoparticle‐Mediated Immunometabolic‐Epigenetic Remodeling Enhances Schwann Cell‐Macrophage Interaction for Sciatic Nerve Regeneration

open access: yesAdvanced Science, EarlyView.
A biomimetic Prussian White nanoparticle (PW) is engineered to achieve long‐term local retention and orchestrate immunometabolic‐epigenetic remodeling for sciatic nerve regeneration. PW directly targets hexokinase 2 to suppress glycolysis, thereby elevating α‐ketoglutarate and driving Kdm4a/b‐mediated demethylation of H3K9me3.
Wenying Xu   +6 more
wiley   +1 more source

Health care crisis: looking beyond the obvious: Part 1: Understanding the forces at play. [PDF]

open access: yesCan Fam Physician
Pilon MD   +5 more
europepmc   +1 more source

Plasma Focus Drive: A Paradox Engine (PE) Hyper-Tech Application

open access: green
Fairweather, Stormy   +3 more
openalex   +1 more source

POU2F1 Promotes Chemoresistance in Colorectal Cancer Cells via Attenuates the MDR2 Degradation Mediated by PPP1R11 Lactylation

open access: yesAdvanced Science, EarlyView.
Schematic diagram of our study showing that highly expressed POU2F1 in colorectal cancer (CRC) can directly accelerate the cytosolic lactate export to decrease PPP1R11 lactylation at K59, thereby attenuating the E3 ligase enzyme activity and protein stability of PPP1R11, which inhibits the ubiquitination of MDR2 at K413 and K538 but increases the ...
Longzheng Xia   +8 more
wiley   +1 more source

Paradoxical pain.

open access: yesBMJ, 1993
Hanks, G W, O'Neill, W M, Fallon, M T
openaire   +3 more sources

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