Breaking the Toughness‐Stretchability Trade‐Off in Hydrogels with Dynamic Hydrogen Bonding
A novel nanocomposite hydrogel architecture overcomes the inherent conflict between toughness and stretchability by integrating uniformly dispersed aminopropyl‐hybrid‐phyllosilicate nanosheets within a polyacrylamide matrix. This design leverages a dynamic hydrogen‐bonding network to facilitate efficient energy dissipation and self‐recovery.
Yining Gao +3 more
wiley +1 more source
Prevalence and paradox: obesity and its comorbid conditions in the modern treatment era. [PDF]
Newman MG.
europepmc +1 more source
Paradojas del duelo en el contexto colombiano. Paradoxes of grief in the colombian context.
Victoria Eugenia Díaz Facio Lince
openalex +2 more sources
In colorectal cancer, high expression of the DNA repair protein EEPD1 correlates with immune exclusion and poor prognosis. This study demonstrates that EEPD1 depletion induces genomic instability, leading to cytosolic DNA accumulation and subsequent activation of the cGAS‐STING‐type I interferon pathway. This cascade remodels the tumor microenvironment
Liyun Huo +8 more
wiley +1 more source
Insight Paradox in Patients With Schizophrenia: A Concept Analysis. [PDF]
Mitsubayashi R, Sugaya T.
europepmc +1 more source
Depletion of p75NTR in Schwann Cells Driven by Inflammation Mediates Cutaneous Pain in Psoriasis
Psoriasis‐like inflammation induces proliferation and molecular remodeling of cutaneous Schwann cells, marked by reduced p75NTR and increased NGF expression. IL‐17A promotes this process, whereas Schwann cell‐specific p75NTR overexpression alleviates cutaneous pain in vivo.
Yibo Wang +9 more
wiley +1 more source
The Obesity Paradox in Hepatocellular Carcinoma: Insights from Continuous and Interaction-Based Analyses of Body Mass Index After Hepatic Resection. [PDF]
Lee B +7 more
europepmc +1 more source
Laterally spreading tumors (LSTs) are precancerous colorectal lesions characterized by a flat morphology. This study reveals a mechanochemical pathway through which a soft matrix microenvironment diminishes spatial constraints in intestinal adenomas. This process promotes deficiencies in tight junction proteins, mediated by the mechanoreceptor ADORA2B ...
Jiamin Zhong +21 more
wiley +1 more source
Synergistic carcinogenesis of the nasopharyngeal microbiome and Epstein-Barr virus: mechanisms of metabolic reprogramming and immune evasion. [PDF]
Shen S, Li J, Zheng S, Cui X, Gou X.
europepmc +1 more source

