Results 111 to 120 of about 9,106 (245)

Ischemia–Reperfusion Injury: Molecular Mechanisms and Therapeutic Interventions

MedComm, Volume 7, Issue 7, July 2026.
Multiorgan ischemia–reperfusion injury begins with ischemia‐induced ATP depletion and ionic imbalance, followed by reperfusion‐triggered mitochondrial ROS/RNS bursts, regulated cell death, and DAMP release. Sterile inflammation converges on endothelial–immune–coagulation crosstalk, where NETs drive immunothrombosis, no‐reflow, and remote organ injury ...
Peng An, Yi An, Mengwei Chen, Longlong Wu, Rong Wang   +4 more
wiley   +1 more source

Follow-up of residual shunt after patent foramen ovale closure [PDF]

, 2010
GRIPPI G, Orzan, F., ORZAN F, Ribezzo, M., Liboni, William, Bonzano, A., Grippi, G., Rebaudengo, N., REBAUDENGO N, Molinari, Filippo, Negri, E., NEGRI E., RIBEZZO M, BONZANO A   +13 more
core   +1 more source

Impending paradoxical embolism: systematic review of prognostic factors and treatment

, 2010
BACKGROUND: Little is known about the optimal management of impending paradoxical embolism (IPDE), a biatrial thromboembolus caught in transit across a patent foramen ovale.
Lerch, René, Myers, Patrick Olivier, Panos, Aristotelis, Bounameaux, Henri, Kalangos, Afksendiyos   +4 more
core   +1 more source

Platelet Transfusion Is Associated With Increased Thrombosis and In‐Hospital Mortality Among Patients Hospitalized With Platelet Consumptive Disorders

European Journal of Haematology, Volume 117, Issue 1, Page 245-257, July 2026.
ABSTRACT Background Platelet transfusion is commonly used to reduce bleeding risk in platelet consumptive disorders. However, platelets may also promote thromboinflammatory pathways, and contemporary data evaluating the association between platelet transfusion, thrombosis, and mortality in this population are limited.
Manas Pustake, Shubhangi Deoker, Veeravenkata Garikiparthy, Kunal Sharma, Lakshmi Kattamuri, Abhizith Deoker, Abhinav Deol   +6 more
wiley   +1 more source

Paradoxical embolism entrapped in a patent foramen ovale

, 2023
Background: According to the Centers for Disease Control (CDC), venous thromboembolisms affect 900,000 people and cause up to 100,000 deaths yearly. A less common subset of these cases includes those of which the emboli, though originating in venous ...
Rowan, Macy, Seibolt, Lucas, Malik, Mohammad, Beaver, Barney   +3 more
core  

Multiaxial Biophysical Control of Oncogenic Phase Separation by Indoleamines: A Proof‐of‐Concept Synthesis of Landscape‐Level Regulation

Journal of Pineal Research, Volume 78, Issue 4, July 2026.
ABSTRACT Oncogenic condensates act as biophysical sanctuaries that stabilize malignant survival programs. However, a universal regulator capable of orchestrating the integrated biophysical axes governing cellular phase behavior has remained elusive.
Doris Loh, Luiz Gustavo de Almeida Chuffa, Fábio Rodrigues Ferreira Seiva, Russel J. Reiter   +3 more
wiley   +1 more source

Positive and Negative Cardiovascular Effects of JAK Inhibitors in Inflammation

ACR Open Rheumatology, Volume 8, Issue 6, June 2026.
Chronic inflammation, characteristic of many autoimmune diseases, such as rheumatoid arthritis (RA), or myeloproliferative neoplasms (MPNs), is an independent driver of accelerated cardiovascular (CV) risk, primarily through proinflammatory cytokines that induce atherosclerosis and endothelial dysfunction.
Aliki Zavoriti, Pierre Miossec
wiley   +1 more source

Impending paradoxical embolism from atrial thrombus: Correct diagnosis by transesophageal echocardiography and prevention by surgery

, 1985
During recovery from a posterolateral myocardial infarction, a 56 year old patient developed signs of deep vein thrombophlebitis and subsequently of pulmonary embolism.
Depping, Karl, Matheis, Günter, Oelert, Hellmut, Nellessen, Ulrich, Daniel, Werner G., Lichtlen, Paul R.   +5 more
core   +1 more source

β‐Adrenergic Signaling Promotes Anti‐Tumor Immunity in TP53‐mutant Oral Squamous Cell Carcinoma

Advanced Science, Volume 13, Issue 35, 24 June 2026.
β‐adrenergic stimulation enhances anti‐tumor immunity in TP53‐deficient oral squamous cell carcinoma by inducing tumor‐derived secretion of CXCL10, which attracts and activates cytotoxic CD8+ T cells. The findings demonstrate that β‐adrenergic signaling alters tumor–immune interactions via CXCL10‐mediated paracrine activation, revealing a neuro‐immune ...
Frederico O. Gleber‐Netto, Deborah Silverman, Tongxin Xie, Shamima Akhter, Nicole R. Vaughn, Adewale Adebayo, Kala Chand Debnath, Shorook Naara, Shajedul Islam, Erik Knutsen, Emily Lorin Ashkin, Simone Anfossi, Sara Leahey, Patrick Hwu, Sebastien Talbot, Erica K Sloan, Robert Saddawi‐Konefka, Roberto Rangel, Jeffrey N. Myers, George A. Calin, Moran Amit   +20 more
wiley   +1 more source

The Risk of Paradoxical Embolism (RoPE) Study: initial description of the completed database

, 2013
BACKGROUND: Detecting a benefit from closure of patent foramen ovale in patients with cryptogenic stroke is hampered by low rates of stroke recurrence and uncertainty about the causal role of patent foramen ovale in the index event.
Di Tullio, Marco R., Serena, Joaquín, Homma, Shunichi, Di Tullio, M.R., Griffith, John, Nedeltchev, K., Elkind, M.S., Mattle, Heinrich P., Mattle, H.P., Elkind, Mitchell S. V., Papetti, F., Papetti, Federica, Mono, M.L., Kent, D.M., Weimar, Christian, Griffith, J., Mono, Marie-Luise, Jaigobin, C., Donovan, Jennifer S., Nedeltchev, Krassen, Michel, Patrik, Mas, Jean-Louis, Di Angelantonio, Emanuele, Jaigobin, Cheryl, Thaler, D.E., Di Angelantonio, E., Kent, David M., Ruthazer, R., Mas, J.L., Ruthazer, Robin, Weimar, C., Serena, J., Thaler, David E., Donovan, J.S., Homma, S., Michel, P.   +35 more
core   +1 more source