Results 111 to 120 of about 482,888 (302)

Effectiveness and safety of cannabidiol in adult patients with epilepsy: A multicenter, retrospective study

Epilepsia Open, EarlyView.
Abstract Objective Cannabidiol (CBD) has demonstrated promising effectiveness and tolerability as adjunctive treatment in patients with severe childhood epilepsies. This study investigated the effectiveness and tolerability of CBD in adults with a history of Dravet syndrome (DS), Lennox–Gastaut syndrome (LGS), or tuberous sclerosis complex (TSC ...
Sara Sánchez‐Gamino, María Isabel Chamorro Muñoz, Pedro J. Serrano‐Castro, Pablo Hernández‐Vitorique, Lucía Rodríguez Jiménez, Yolanda López Moreno, Pablo Cabezudo‐García, Guillermina García Martín   +7 more
wiley   +1 more source

Paradoxical Interventions in Psychotherapy: A Scoping Review on ‘How’ and ‘When’ They Should Be Employed

Psychiatry International
There is solid evidence supporting the therapeutic effectiveness of paradoxical interventions, those in which the patient is encouraged to maintain or increase the behavior or thought that s/he wants to remove. However, their use in recent years has been
José V. Viguer, Amelia Díaz, Martha Martín   +2 more
doaj   +1 more source

CLINICAL ASPECTS OF SLEEP DISORDERS IN PATIENTS WITH PARKINSON’S DISEASE

Клиническая практика, 2017
According to the scientific literature of sleep disturbance in patients with Parkinson’s disease meet from 51 to 85 %. In this study, PD patients with sleep disturbances were found in 50.1% (348 of 694 patients) were included in the registry (it surveyed
O A Andrienko
doaj   +1 more source

The Pituitary-Adrenal Response to Paradoxical Sleep Deprivation Is Similar to a Psychological Stressor, Whereas the Hypothalamic Response Is Unique. [PDF]

Front Endocrinol (Lausanne), 2022
Moraes DA, Machado RB, Koban M, Hoffman GE, Suchecki D.   +4 more
europepmc   +1 more source

Crosstalk Between Parkinson's Disease and Colorectal Cancer: Genetic Mechanisms, Gut Microbiota, and Therapeutic Insights

Health Care Science, EarlyView.
This review elucidates the crosstalk between Parkinson's disease and colorectal cancer, driven by shared genetics (PRKN, PINK1, DJ‐1) involving oxidative stress, cell cycle regulation, and inflammation. It identifies the gut microbiota—via functional amyloids and short‐chain fatty acids (SCFAs)—as a mechanistic bridge, offering insights for dual ...
Jiacheng Ying, Zhengyuan Fang, Cheng Zhang, Xu Liu, Jianzhi Cui, Zezhi Li, Jiayin Tang   +6 more
wiley   +1 more source

A deep learning software tool for automated sleep staging in rats via single channel EEG

NPP-Digital Psychiatry and Neuroscience
Poor quality and poor duration of sleep have been associated with cognitive decline, diseases, and disorders. Therefore, sleep studies are imperative to recapitulate phenotypes associated with poor sleep quality and uncover mechanisms contributing to ...
Andrew Smith, Snezana Milosavljevic, Courtney J. Wright, Charlie A. Grant, Ana Pocivavsek, Homayoun Valafar   +5 more
doaj   +1 more source

Sleep-related consolidation of a visuomotor skill: brain mechanisms as assessed by functional magnetic resonance imaging [PDF]

, 2003
Subjects were trained on a pursuit task in which the target trajectory was predictable only on the horizontal axis. Half of them were sleep deprived on the first post-training night (n = 13).
Frith, Christopher, Maquet, P, Frith, C, Christopher Frith, Pierre Maquet, Maquet, Pierre, Passingham, R, Schwartz, Sophie, Sophie Schwartz, Schwartz, S, Richard Passingham, Passingham, Richard   +11 more
core   +1 more source

Health System Resilience and Afghan Refugee Health in Pakistan: An Exploratory Study of Challenges and Pathways to Inclusion

The International Journal of Health Planning and Management, EarlyView.
ABSTRACT Pakistan has hosted Afghan refugees for more than four decades, in one of the world's most protracted displacements of people. Afghan refugees receive health services through United Nations High Commissioner for Refugees (UNHCR) and non‐governmental organisation (NGO) supported programmes alongside public sector facilities at every tier.
Zahid Ali Memon, Asma Ummad, Amina Olabi, Natasha Palmer, Sophie Witter   +4 more
wiley   +1 more source

Effect of paradoxical sleep deprivation and stress on passive avoidance behavior

, 2003
Previous studies have shown that several types of stress can induce memory impairment. However, the memory effects of paradoxical sleep deprivation (PSD), a stressor in itself, are unclear.
Wang, JH, Tian, SW, Ma, YY, J. Hong Wang, Y. Ye Ma, van den Buuse, M   +5 more
core   +1 more source

Increased de novo glutathione production enhances sexual dysfunctions in rats subjected to paradoxical sleep deprivation. [PDF]

JBRA Assist Reprod, 2021
Medubi LJ, Nwosu NC, Medubi OO, Lawal OR, Ama C, Kusemiju TO, Osinubi AA.   +6 more
europepmc   +1 more source