Results 131 to 140 of about 482,888 (302)

Successful Co‐Administration of Secukinumab and Dupilumab in a Patient With Psoriasis and Paradoxical Atopic Dermatitis

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Paradoxical atopic dermatitis (AD) can arise during biologic therapy for psoriasis due to an immune‐axis imbalance. We describe a 47‐year‐old man who developed severe AD while receiving secukinumab, which was successfully managed with the addition of dupilumab, allowing long‐term control of both diseases.
So Yun Park   +6 more
wiley   +1 more source

Sleep deprivation in the rat: XX. Differences in wake and sleep temperatures during recovery

open access: yes, 1995
We examined the relationship between wake and sleep peritoneal temperature (T(ip)) during recovery from short-term (five rats, 5 days of deprivation) and long-term (nine rats, 14-21 days) total sleep deprivation (TSD). Mammalian body temperature normally
Feng, P. F.   +6 more
core   +1 more source

Paradoxical Alopecia Areata Induced by IL‐17 and IL‐23 Inhibitors: A Systematic Review

open access: yesJEADV Clinical Practice, EarlyView.
This systematic review identifies consistent clinical patterns of alopecia areata associated with IL‐17 and IL‐23 inhibitors, most frequently involving secukinumab and ustekinumab. Disease severity varied widely, and management often required biologic discontinuation or therapeutic switching.
Isabella Kamholtz   +2 more
wiley   +1 more source

Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity: Pathogenesis, Diagnostics, Risk Stratification, and Therapeutic Approach

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, closely linked to the global rising incidence of obesity and metabolic syndrome. This review synthesizes current evidence on the pathogenesis, gut–liver axis, and multidisciplinary management of MASLD within the ...
Beom Kyung Kim
wiley   +1 more source

Self-grooming, experimental anxiety and paradoxical sleep deprivation in rats

open access: yes, 2012
Objective: Paradoxical sleep deprivation increases grooming behaviors in rats. Discordant data on the change promoted by such deprivation on the experimentally defined anxiety levels have made difficult to assess if the deprivation induced grooming may ...
Pezzato, Fernanda Augustini [UNESP]   +2 more
core  

A Novel BHLHE41 Variant is Associated with Short Sleep and Resistance to Sleep Deprivation in Humans

open access: yes, 2014
Study Objectives: Earlier work described a mutation in DEC2 also known as BHLHE41 (basic helix-loop-helix family member e41) as causal in a family of short sleepers, who needed just 6 h sleep per night.
Dinges, David F   +19 more
core   +1 more source

Knowledge Gaps, Treatment Preferences, and Unmet Clinical Needs Among Patients With Inflammatory Bowel Disease: A Cross‐Sectional Study

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study utilized a cross‐sectional survey via a structured questionnaire to evaluate disease‐related knowledge, treatment preferences, and unmet needs among 200 adults with confirmed inflammatory bowel disease (IBD) at a tertiary referral center.
Yi‐Chen Wu   +11 more
wiley   +1 more source

Characteristics of the sleep structure in the cleaner wrasse Labroides dimidiatus

open access: yesZoological Letters
Sleep is a widespread phenomenon among animals, yet its evolutionary traits and core functions remain largely enigmatic. To elucidate the fundamental characteristics of behavioral sleep in fish, we conducted quantitative assessments of behavioral and ...
Masayuki Yoshida   +4 more
doaj   +1 more source

Free Recall of Word Lists under Total Sleep Deprivation and after Recovery Sleep

open access: yes, 2012
Study Objectives: One task that has been used to assess memory effects of prior total sleep deprivation (TSD) is the immediate free recall of word lists; however, results have been mixed.
Pompeia, Sabine [UNIFESP]   +6 more
core   +1 more source

Race and Ethnicity Affect Symptom and Endoscopy Associations in CT‐Confirmed Chronic Rhinosinusitis

open access: yesThe Laryngoscope, EarlyView.
Among adults with chronic rhinosinusitis (CRS) symptoms, hyposmia, and higher Lund–Kennedy endoscopy scores were associated with CT‐confirmed CRS overall, though these associations were not significant among Asian and Hispanic patients. Symptoms alone had limited predictive value when nasal endoscopy was negative, suggesting that the diagnostic utility
Corey Karp   +6 more
wiley   +1 more source

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