Results 131 to 140 of about 87,311 (279)

Opioids in breast cancer: Between analgesia and modulation of tumour progression

open access: yesBritish Journal of Pharmacology, EarlyView.
Preclinical investigations consistently demonstrate that activation of μ‐opioid receptors and δ‐opioid receptors promote proliferation, migration, angiogenesis, epithelial‐mesenchymal transition, acquisition of cancer stem cell phenotypes, and chemoresistance.
Marianna Ciwun   +2 more
wiley   +1 more source

Letter to the Editor: Redesigning mental health support for youth – early interventions need to move away from the diagnostic model

open access: yesChild and Adolescent Mental Health, EarlyView.
The recent stimulating debate series in CAMH has highlighted how efforts to raise mental health awareness have resulted in a paradox: overpathologisation is a concern, and yet timely recognition and access to evidence‐based support remain insufficient. Often those who need help most are least likely to access it.
Maria E. Loades
wiley   +1 more source

Sleep, Wakefulness, Dreams and Memory [PDF]

open access: yes
Sleep-wakefulness cycle mechanisms shown in central neural activity ...
Koella, W. P., Nauta, W. J. H.
core   +1 more source

Technical, Cultural and Religious: Risks for Children in Minority Religious Communities as Seen in the Ultra‐Orthodox Jewish Community During COVID‐19

open access: yesChild &Family Social Work, EarlyView.
ABSTRACT Child development research predominantly focuses on Western secular contexts and does not adequately consider non‐Western religious contexts. The COVID‐19 pandemic has affected children worldwide in various dimensions, with children from minority populations being disproportionately impacted.
Netanel Gemara
wiley   +1 more source

Defensive medicine in dermatological practice – Dermatopathology as a mirror of structural challenges

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Defensive medicine refers to diagnostic or therapeutic actions taken primarily to reduce legal liability rather than to benefit the patient. In dermatopathology, defensive practices manifest in frequent immunohistochemical testing, overly cautious report phrasing, and reliance on multidisciplinary tumor boards.
Cornelia Sigrid Lissi Müller   +2 more
wiley   +1 more source

The absence of Neuroligin-1 shapes wake/sleep architecture, rhythmic and arrhythmic activities of the electrocorticogram in female mice

open access: yesMolecular Brain
Associated to glutamatergic neurotransmission, Neuroligin-1 (NLGN1) is a synaptic adhesion molecule with roles in the regulation of behavioral states and cognitive function.
Cassandra C. Areal   +6 more
doaj   +1 more source

Non‐epileptic paroxysmal events in Rett syndrome: A systematic review of case‐based and observational evidence

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
This systematic review identifies and categorizes the spectrum of non‐epileptic paroxysmal events in Rett syndrome. Respiratory disturbances, behavioural episodes, and motor events were the most commonly reported. Improving clinician awareness and diagnostic clarity is key to avoiding unnecessary treatment and enhancing quality of life for individuals ...
Natasha Bhatti, Daniel E. Lumsden
wiley   +1 more source

Aerospace Medicine and Biology: A continuing bibliography with indexes [PDF]

open access: yes
This bibliography lists 253 reports, articles, and other documents introduced into the NASA scientific and technical information system in October ...

core   +1 more source

Effectiveness and adherence in a tirzepatide‐supported digital weight‐loss programme in Australia: A real‐world observational study

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Obesity is a growing global health crisis; pharmacotherapies such as tirzepatide combined with multidisciplinary lifestyle support have shown promise but real‐world evidence in digital weight‐loss services (DWLSs) is limited. This retrospective study evaluated 6‐ and 12‐month weight loss, adherence and predictors of outcomes in an ...
Louis Talay   +3 more
wiley   +1 more source

Light as a chronobiologic countermeasure for long-duration space operations [PDF]

open access: yes
Long-duration space missions require adaptation to work-rest schedules which are substantially shifted with respect to earth. Astronauts are expected to work in two-shift operations and the environmental synchronizers (zeitgebers) in a spacecraft differ ...
Evans, Julie   +9 more
core   +1 more source

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