Results 141 to 150 of about 87,517 (277)

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

British Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli, Emanuela Micioni Di Bonaventura, Giacomo Einaudi, Gustavo Provensi, Alessia Costa, Claudio D'Addario, Carlo Cifani, Maria Vittoria Micioni Di Bonaventura   +7 more
wiley   +1 more source

Opioids in breast cancer: Between analgesia and modulation of tumour progression

British Journal of Pharmacology, EarlyView.
Preclinical investigations consistently demonstrate that activation of μ‐opioid receptors and δ‐opioid receptors promote proliferation, migration, angiogenesis, epithelial‐mesenchymal transition, acquisition of cancer stem cell phenotypes, and chemoresistance.
Marianna Ciwun, Anna Tankiewicz‐Kwedlo, Dariusz Pawlak   +2 more
wiley   +1 more source

The absence of Neuroligin-1 shapes wake/sleep architecture, rhythmic and arrhythmic activities of the electrocorticogram in female mice

Molecular Brain
Associated to glutamatergic neurotransmission, Neuroligin-1 (NLGN1) is a synaptic adhesion molecule with roles in the regulation of behavioral states and cognitive function.
Cassandra C. Areal, Nicolas Lemmetti, Tanya Leduc, Clément Bourguignon, Jean-Marc Lina, Erika Bélanger-Nelson, Valérie Mongrain   +6 more
doaj   +1 more source

Letter to the Editor: Redesigning mental health support for youth – early interventions need to move away from the diagnostic model

Child and Adolescent Mental Health, EarlyView.
The recent stimulating debate series in CAMH has highlighted how efforts to raise mental health awareness have resulted in a paradox: overpathologisation is a concern, and yet timely recognition and access to evidence‐based support remain insufficient. Often those who need help most are least likely to access it.
Maria E. Loades
wiley   +1 more source

Technical, Cultural and Religious: Risks for Children in Minority Religious Communities as Seen in the Ultra‐Orthodox Jewish Community During COVID‐19

Child &Family Social Work, EarlyView.
ABSTRACT Child development research predominantly focuses on Western secular contexts and does not adequately consider non‐Western religious contexts. The COVID‐19 pandemic has affected children worldwide in various dimensions, with children from minority populations being disproportionately impacted.
Netanel Gemara
wiley   +1 more source

Prevalence of Buccal Ridge Concavities Following Implant Placement With Contour Bone Augmentation: A Cross‐Sectional Study

Clinical Oral Implants Research, EarlyView.
ABSTRACT Objectives To evaluate the long‐term prevalence of buccal ridge concavity (BRC) following implant placement with simultaneous contour bone augmentation (CBA). Methods Adult patients with at least one single‐tooth non‐molar implant‐supported prosthesis and no diagnosis of peri‐implantitis were included in this exploratory cross‐sectional study.
Sophia E. Vollath, Giorgina M. Wiedmer, Clemens Raabe, Manrique Fonseca, Vivianne Chappuis, Maria B. Asparuhova, Ningbo Zhao, Emilio Couso‐Queiruga   +7 more
wiley   +1 more source

Cytokine and microRNA levels during different periods of paradoxical sleep deprivation and sleep recovery in rats. [PDF]

PeerJ, 2018
Brianza-Padilla M, Sánchez-Muñoz F, Vázquez-Palacios G, Huang F, Almanza-Pérez JC, Bojalil R, Bonilla-Jaime H.   +6 more
europepmc   +1 more source

Impact of Allergic Contact Dermatitis on Health‐Related Quality of Life: A Cross‐Sectional Case–Control Study in a Spanish Population

Contact Dermatitis, EarlyView.
Allergic contact dermatitis markedly impairs quality of life (QoL) across symptoms, functioning and emotional domains. Using DLQI, Skindex‐29 and EQ‐5D‐5L, our study demonstrates a substantial multidimensional burden and highlights the need for routine, patient‐centred QoL assessment in clinical management.
Francisco José Navarro‐Triviño, Álvaro Prados‐Carmona, Ricardo Ruiz‐Villaverde, María Isabel Peralta‐Ramírez   +3 more
wiley   +1 more source

Book Review: The Presidency of Abraham Lincoln, by Phillip Shaw Paludan

, 1996
Americans have had a highly complex love-hate relationship with politics, especially with political ideology. Recent books on the state of American politics underscore the resentment Americans feel at governments that have grown bloated and indifferent ...
Guelzo, Allen C.
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