Results 41 to 50 of about 87,311 (279)

Increased Risk of Ischemic Stroke during Sleep in Apneic Patients. [PDF]

open access: yes, 2018
BACKGROUND AND PURPOSE:The literature indicates that obstructive sleep apnea (OSA) increases the risk of ischemic stroke. However, the causal relationship between OSA and ischemic stroke is not well established.
Im, Kyoung Bin   +5 more
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Comparative Perspectives that Challenge Brain Warming as the Primary Function of REM Sleep

open access: yesiScience, 2020
Summary: Rapid eye movement (REM) sleep is a paradoxical state of wake-like brain activity occurring after non-REM (NREM) sleep in mammals and birds.
Gianina Ungurean   +4 more
doaj   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Wide-spread brain activation and reduced CSF flow during avian REM sleep

open access: yesNature Communications, 2023
Mammalian sleep has been implicated in maintaining a healthy extracellular environment in the brain. During wakefulness, neuronal activity leads to the accumulation of toxic proteins, which the glymphatic system is thought to clear by flushing cerebral ...
Gianina Ungurean   +6 more
doaj   +1 more source

Sleep and Paradoxical Sleep in Ruminants.

open access: yesExperimental Biology and Medicine, 1966
SummaryThis study proved that ruminants have the physiologic capacity for sleep and paradoxical sleep. Daytime ruminant sleep in goats was transient and polyphasic, averaging 5.1 ± 0.6 minutes per episode. The frequency was variable, ranging from 0 to 6 episodes during daytime.
openaire   +2 more sources

Preclinical discovery of duloxetine for the treatment of depression [PDF]

open access: yes, 2012
Introduction: Affective disorders, including major depressive disorder (MDD), are among the most severely disabling mental disorders, and in many cases areIntroduction: Affective disorders, including major depressive disorder (MDD), are among the most ...
Berrocoso Domínguez, Esther María   +4 more
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Comparison of Triple Combination Oral Sedation Regimens for Pediatric Dental Treatment [PDF]

open access: yes, 2019
Purpose: Compare the efficacy of two benzodiazepines (diazepam or midazolam) in combination with meperidine and hydroxyzine for pediatric dental sedation.
Henderson, Brett H
core   +1 more source

Risk factors for obstructive sleep apnea syndrome in children: state of the art [PDF]

open access: yes, 2019
The obstructive sleep apnea syndrome (OSAS) represents only part of a large group of pathologies of variable entity called respiratory sleep disorders (RSD) which include simple snoring and increased upper airway resistance syndrome (UARS).
Bellini, Chiara   +16 more
core   +2 more sources

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