Results 51 to 60 of about 87,311 (279)

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Paradoxical sleep deprivation increases plasma endothelin levels

Brazilian Journal of Medical and Biological Research, 2002
The endothelins (ET-1, 2 and 3) constitute a family of 21 amino acid peptides with potent biological activities. ET-1 is one of the most potent endogenous vasoconstrictors so far identified and its increased concentration in plasma appears to be closely ...
B.D. Palma, A. Gabriel Jr., M. Bignotto, S. Tufik   +3 more
doaj   +1 more source

CD27 and ICOS as Targets of PD‐1/PD‐L1 Signaling to Regulate Resident Memory CD8+ T‐Cell‐Mediated Pulmonary Protection and Pathology

Advanced Science, EarlyView.
Here it is revealed that the costimulatory receptors CD27 and ICOS are essential for the long‐term maintenance of PD‐1high CD8+ TRM cells following influenza infection. PD‐L1 blockade enhances the proliferation and activation of these cells through Nur77 activation downstream of the CD27/ICOS signaling axis, thereby boosting host immunity against ...
Yuanyuan Chen, Zhenzhen Wang, Liqiang Song, Qianqian Chen, Hang Zhang, Tao Pan, Jianli Pan, Sheng Zhao, Ting Shang, Hong'en Xu, Xing Lv, Jing Li, Fei Kang, Yongzhan Nie, Feng Zhao, Lei Shi, Zheng Wang   +16 more
wiley   +1 more source

Nonlinear aspects of the EEG during sleep in children [PDF]

, 2005
Electroencephalograph (EEG) analysis enables the neuronal behavior of a section of the brain to be examined. If the behavior is nonlinear then nonlinear tools can be used to glean information on brain behavior, and aid in the diagnosis of sleep ...
Abbott, Derek, Allison, Andrew, Berryman, Matthew J., Coussens, Scott W., Kennedy, Declan, Lushington, Kurt, Martin, A. James, Pamula, Yvonne, Saint, David, Shalizi, Cosma   +9 more
core   +4 more sources

Photoacoustic Microscopy for Multiscale Biological System Visualization and Clinical Translation

Advanced Science, EarlyView.
Photoacoustic microscopy (PAM) is a powerful biomedical imaging tool renowned for its non‐invasiveness and high resolution. This review synthesizes recent technological advances and highlights their broad applications from cellular and organ‐level to whole‐animal imaging.
Tingting Wang, Jiali Chen, Liming Nie, Honghui Li   +3 more
wiley   +1 more source

SLEEPING – AN EFFICIENT WAY OF PERFORMANCE SPORTSMEN RECOVERING [PDF]

Annals of the “Ştefan cel Mare” University: Physical Education and Sport Section - The Science and Art of Movement, 2019
Sleeping is a brain activity state characterized by temporary interruption of conscient touch with the exterior and interior, being a reverse state.
Juravle Mariana
doaj  

Effect of various inductions of sleep deprivation stress on proinflammatory cytokine levels in gingival crevicular fluids of white male Wistar strain rats (Rattus novergicus)

Dental Journal, 2020
Background: Stress that is induced by sleep deprivation can modulate the damage of periodontal tissue by elevating the levels of proinflammatory cytokines (i.e. IL-1β and TNF-α).
Pratiwi Nur Widyaningsih, Fitranto Arjadi, Erlina Sih Mahanani   +2 more
doaj   +1 more source

Parents' WhatsApp coping resources in the context of ongoing political conflicts: An ecological exploration

American Journal of Community Psychology, EarlyView.
Abstract Mobile technologies have become significant resources for crisis communication and social support in recent years. However, despite empirical evidence pointing to the centrality of these technologies for parenthood in everyday life, it is yet unknown how parents' coping resources play a role in the digital environment.
Daphna Yeshua‐Katz, Stav Shapira, Orna Braun‐Lewensohn   +2 more
wiley   +1 more source

How are normal sleeping controls selected? A systematic review of cross-sectional insomnia studies, and a standardised method to select healthy controls for sleep research [PDF]

, 2008
There appears to be some inconsistency in how normal sleepers (controls) are selected and screened for participation in research studies for comparison with insomnia patients.
Louise Beattie, Colin A. Espie, Simon D. Kyle, Stephany M. Biello, Luyster, Edinger, Heffner, American Sleep Disorders Association, Buysse, Bastien, Ong, Bower, Ree, Barclay, Jones, Horne, Archer, Goel, Taillard, Phipps-Nelson, Carney, Vandewalle, Yoo, Ferguson, Buysse, Dahlgren, Carney, Buysse, Espie, Espie, Lund, Yiend, Espie, Harvey, Harvey, Kyle, Ellis, Ohayon, Barclay, Monk, Barclay, Monk, Wittmann, Roenneberg, Spiegel, Kyle, Lineberger, Wilson, Doghamji, Douglass, Baumann, Espie, Buysse, Meerlo, Kripke, Vgontzas, Kaplan, Van Dongen, Monk, Drake   +59 more
core   +5 more sources

T. rex cognition was T. rex‐like—A critical outlook on diverging views of the neurocognitive evolution in dinosaurs

The Anatomical Record, EarlyView.
Abstract A recent debate has emerged between Caspar et al. (2024) and Herculano‐Houzel (2023) on inferring extinct dinosaur cognition by estimating brain neuron counts. While thought‐provoking, the discussion largely overlooks the function of cognition, as well as partly neglects the difficulties involved in estimating neuron numbers, which according ...
Thomas Rejsenhus Jensen, Ivo Jacobs, Kristina Kverková, Lona Lalić, Alexandra Polonyiová, Patrik Stehlík, Stephan A. Reber, Mathias Osvath   +7 more
wiley   +1 more source