Results 271 to 280 of about 891,439 (340)

3D Bioprinted Human Synovium‐Cartilage Models Mimic Rheumatoid Arthritis Microenvironment and Recapitulate In Vivo Therapeutic Responses

Advanced Materials, EarlyView.
This study presents human in vitro rheumatoid arthritis models using chondrocytes recellularized type II collagen scaffold and 3D‐bioprinted Gelatin‐Matrigel hydrogels with fibroblast‐like synoviocytes, pro‐inflammatory macrophages, and protective barrier macrophages, closely recapitulating key rheumatoid arthritis pathological features.
Huiqun Zhou, Zhen Zhang, Yulei Mu, Liang Ma, Xu Hu, Bangheng Liu, Dong‐An Wang   +6 more
wiley   +1 more source

Comparative Evaluation of Spreadability Measurement Methods for Topical Semisolid Formulations/A Scoping Review. [PDF]

Gels
Al-Barghouthy EY, Hamed S, Mehyar GF, AlKhatib HS.   +3 more
europepmc   +1 more source

Mesenchymal Stem Cell‐Inspired Microneedle Platform for NIR‐responsive Immunomodulation and Accelerated Chronic Wound Healing

Advanced Materials, EarlyView.
The research demonstrates a Mesenchymal Stem Cell‐inspired microneedle platform (MSCi@MN) that addresses chronic diabetic wounds by combining MSC‐derived extracellular nanovesicles (NV)–DNA conjugates in microneedle tips with photothermal MXene in the patch layer.
Chan Ho Moon, Hee Gyeong Ko, Hyun Lee, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Jong Hwa Seo, Nayoung Lee, So Won Jeon, Yun‐A Kim, Jong Sang Yoon, Kyung‐Yup Cha, Min‐Ho Kang, Dong Yun Lee, Soo‐Hong Lee, Gi Doo Cha, Kisuk Yang, Donghyun Lim, Heemin Kang, Su Ryon Shin, Han Young Kim, Hyun‐Do Jung   +21 more
wiley   +1 more source

Properties of paraffin wax as a bolus material in accelerator-based boron neutron capture therapy. [PDF]

Acta Oncol
Tarvonen J, Wendland L, Porra L, Seppälä T, Tenhunen M.   +4 more
europepmc   +1 more source

A Wearable, Dual Closed‐loop Insulin Delivery System for Precision Diabetes Management

Advanced Materials, EarlyView.
A wearable dual closed‐loop drug delivery system for diabetes management is presented, featuring an adaptive, on‐body trained edge AI algorithm for precise insulin delivery, which enhances therapeutic accuracy from 92.10% to 98.82%. Abstract Effective blood glucose management is an increasing demand worldwide.
Xuecheng He, Wei Huang, Wensheng Lin, Binbin Cui, Xinyu Tian, Jing Bai, Dingyao Liu, Ivo Pang, Hao Huang, Shixian Lin, Jixiang Zhu, Jinqiang Wang, Shiming Zhang   +12 more
wiley   +1 more source

Assessment of target-enrichment library preparation and next-generation sequencing of paraffin-embedded gastric biopsies for H. pylori diagnosis and evaluation of virulome and resistome. [PDF]

Sci Rep
Gillet L, Perreau C, Bruhl L, Jehanne Q, Marty M, Rauturier M, Belleannée G, Parrens M, Dubus P, Lehours P.   +9 more
europepmc   +1 more source

Operando X‐ray Spectroscopy Study of Pd and Pd–Au Laterally Condensed Catalysts during Selective Acetylene Hydrogenation: The Role of Carbon

Advanced Materials, EarlyView.
The selective hydrogenation of acetylene over laterally condensed Pd and Pd–Au catalysts (LCCs) was investigated using operando X‐ray absorption and photoelectron spectroscopy in combination with density functional theory. Pd‐LCCs were found to incorporate significantly more carbon into the metal lattice than Pd–Au LCCs, where the carbon uptake governs
Eylül Öztuna, Thomas Götsch, Daniel Cruz, Patrick Zeller, Olga V. Vinogradova, Zehua Li, Christian Rohner, Franz‐Philipp Schmidt, Zahra Gheisari, Alexander Steigert, Martin Muske, Michael Hävecker, Eugen Stotz, Iryna Antonyshyn, Frank Girgsdies, Olaf Timpe, Thomas Lunkenbein, Vanessa J. Bukas, Karsten Reuter, Robert Schlögl, Katarzyna Skorupska, Axel Knop‐Gericke, Beatriz Roldán Cuenya   +22 more
wiley   +1 more source

Clinicopathological data and the role of miRNA expression in patients with pheochromocytomas/paragangliomas. [PDF]

Front Endocrinol (Lausanne)
Thanasoula F, Yavropoulou MP, Kyriakopoulos G, Papatheodorou A, Maltezos C, Maltezos K, Vasileiou V, Kassi E, Kaltsas G, Angelousi A.   +9 more
europepmc   +1 more source

Potent Liver‐Tropic mRNA Lipid Nanoparticles: ApoE‐Mediated Delivery Through a Low‐Density Lipoprotein Receptor Independent Uptake Mechanism

Advanced Materials, EarlyView.
Helper and ionizable lipids play a crucial role in determining ApoE binding and subsequent liver tropism and LDLR‐mediated uptake. Ionizable lipids primarily govern the LDLR‐independent uptake pathway. This complementary interplay between lipid components ultimately governs LNP delivery performance and therapeutic efficacy in the liver.
Ashish Sarode, Christian Ortiz, Tadeh Derstepanian, Natalia Vargas‐Montoya, Priyal Patel, Nikita Khadse, Saikat Manna, Ryan Landis, Joseph Skaleski, Lianne Boeglin, Hongfeng Deng, Anusha Dias, Hong Wang, Debora Barreiros Petropolis, Barak Yahalom, Shrirang Karve, Frank DeRosa   +16 more
wiley   +1 more source