Advanced Science, Volume 13, Issue 26, 8 May 2026.Lipid overload suppresses SREBF2‐mediated FNTB expression, leading to defective Lamin A maturation and nuclear envelope instability. This nuclear catastrophe triggers a pro‐fibrotic senescence program in cardiomyocytes. Notably, restoring nuclear integrity via AAV9‐based gene therapy effectively attenuates cardiac remodeling, identifying the ...
Yuxiao Chen +16 more
wiley +1 more source
Household fuel use and severe asthma symptoms among preschool children in Gauteng province, South Africa: a cross-sectional study. [PDF]
BMJ Public HealthBhuda M, Wichmann J, Shirinde J.
europepmc +1 more source
Advanced Science, Volume 13, Issue 26, 8 May 2026.This study delineates macrophage heterogeneity along the acute kidney injury to chronic kidney disease transition. Single‐cell RNA sequencing reveals a TRAP5+ scar‐associated macrophage subset driven by Spp1–Cd44 signaling and mitochondrial metabolic reprogramming.
Chenxi Wang +13 more
wiley +1 more source
Enhanced Energy Storage Properties of Building Insulation Materials via Supplementing with EG/PA Composite Phase-Change Materials. [PDF]
ACS OmegaYang H, Zhang Y, Cui B.
europepmc +1 more source
Dysregulation of the PATZ1/CTCF Balance Silences ZBTB20 to Drive Melanoma Progression
Advanced Science, Volume 13, Issue 26, 8 May 2026.This study uncovers a new oncogenic mechanism in melanoma. The transcription factor PATZ1 competes with the architectural protein CTCF for DNA binding, thereby disrupting a specific chromatin loop and silencing the tumor suppressor ZBTB20. This event unleashes the pro‐tumorigenic PMEPA1‐p38‐STAT1 signaling axis, promoting cancer progression.
Chaowei Deng +8 more
wiley +1 more source
Reclaiming Ruthenium: A Comprehensive Review of Hydrometallurgical Strategies for Precious Metal Recovery. [PDF]
Materials (Basel)Rudnik E.
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Health Basket and Health Block Grants Guidelines for the Disbursement of Funds, Preparation of Comprehensive Council Health Plans, Financial and Technical Reports and Rehabilitation of PHC Facilities by Councils [PDF]
, 2004 Ministry of Health and Social Welfare, (MoHSW) +1 more
core
Advanced Science, Volume 13, Issue 26, 8 May 2026.A dual‐targeting strategy to rejuvenate aged tendons. A reactive oxygen species (ROS)‐responsive hydrogel co‐delivers a selenium nanozyme (scavenges ROS) and a STING inhibitor to tendon stem cells. This combined action restores mitochondria–nucleus communication, alleviates cellular senescence, and rejuvenates tendon regeneration, offering a novel ...
Zhuo Zhang +11 more
wiley +1 more source
Mitigating thermal runaway in EV batteries using hybrid energy storage and phase change materials. [PDF]
RSC AdvTalha M, Palange R, Khan SA, DeBlasio C.
europepmc +1 more source
Advanced Science, Volume 13, Issue 25, 4 May 2026.A biomimetic Prussian White nanoparticle (PW) is engineered to achieve long‐term local retention and orchestrate immunometabolic‐epigenetic remodeling for sciatic nerve regeneration. PW directly targets hexokinase 2 to suppress glycolysis, thereby elevating α‐ketoglutarate and driving Kdm4a/b‐mediated demethylation of H3K9me3.
Wenying Xu +6 more
wiley +1 more source