Results 51 to 60 of about 48,277 (262)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

WAX PARAFFIN FILM IN THE TREATMENT OF BURNS [PDF]

Journal of the American Medical Association, 1917
Following the suggestion of Dr. D'Arcy Power, and using his formulas for a film, I have completed treatment in 100 out of about 250 cases treated. After the hundredth case I ceased to record the histories. The treatment was used in certain selected cases in which it seemed most indicated.
openaire   +2 more sources

Simulating Paraffin Wax Deposit Removal: A Numerical Study of SGN Application [PDF]

Journal of Applied and Computational Mechanics
Offshore oil exploration encounters numerous challenges, the formation of paraffin wax deposits ranks among them. The Nitrogen Generating System (SGN) emerges as a hybrid technique, utilizing a thermochemical reaction with nitrogen salts to generate heat
Rafael Cavalcante, Julio Cesar Dutra, Luiz Alberto Abreu, Diego Estumano, Evaldiney Monteiro, Wellington da Silva   +5 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Conditioning banana sheath fibers using paraffin and micro wax to form creative products

Case Studies in Chemical and Environmental Engineering
This research study assessed the physical properties of banana sheath fibers coated with micro wax to form creative products. The fibers of two banana species, Kluai Hom Thong and Kluai Nam Wa were coated with micro wax at 0, 50, and 100 % of paraffin ...
Sopida Wisansakkul, Orawan Oupathumpanont   +1 more
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Characterization of Fast-Scan Cyclic Voltammetric Electrodes Using Paraffin as an Effective Sealant with In Vitro and In Vivo Applications. [PDF]

PLoS ONE, 2015
Fast-scan cyclic voltammetry (FSCV) is a powerful technique for measuring sub-second changes in neurotransmitter levels. A great time-limiting factor in the use of FSCV is the production of high-quality recording electrodes; common recording electrodes ...
Eric S Ramsson, Daniel Cholger, Albert Dionise, Nicholas Poirier, Avery Andrus, Randi Curtiss   +5 more
doaj   +1 more source

Strain‐Programmable Luminescent Adhesive Patch With Tartrazine‐Mediated Optical Skin Clearing for Photochemical Tissue Bonding

Advanced Functional Materials, EarlyView.
We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim, Kyungjoo Jo, Kwanghyeon Park, Jun Hee Kim, Jong Hyeong Cho, Inhoo Choi, Sei Kwang Hahn   +6 more
wiley   +1 more source

Snap‐Through–Driven Liquid Crystal Elastomers for High‐Power Remote Microneedle Actuation Toward Smart Livestock Systems

Advanced Functional Materials, EarlyView.
A magnetically assisted snap‐through liquid crystal elastomer transforms photochemical deformation into a high‐power mechanical impulse, enabling remote microneedle actuation and highlighting its potential for future smart livestock intervention systems.
Chae Won Lee, Nankyung Kim, SeungHyun Park, Dae Seok Kim   +3 more
wiley   +1 more source

Experimental studies on underwater self-inhaled sealing state of phase change materials

Shuili Shuiyun Gongcheng Xuebao, 2019
Under extreme conditions such as flood season, leakage is the precursor of dam burst and dam break. The key measure to cut off the disaster chain of dam break is emergency handling of leakage timely and effectively.
ZHANG Shenghang, TANG Lei, JIA Yu, WANG Yulei   +3 more
doaj   +1 more source