Results 61 to 70 of about 92,347 (295)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Simulating Paraffin Wax Deposit Removal: A Numerical Study of SGN Application [PDF]

open access: yesJournal of Applied and Computational Mechanics
Offshore oil exploration encounters numerous challenges, the formation of paraffin wax deposits ranks among them. The Nitrogen Generating System (SGN) emerges as a hybrid technique, utilizing a thermochemical reaction with nitrogen salts to generate heat
Rafael Cavalcante   +5 more
doaj   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Conditioning banana sheath fibers using paraffin and micro wax to form creative products

open access: yesCase Studies in Chemical and Environmental Engineering
This research study assessed the physical properties of banana sheath fibers coated with micro wax to form creative products. The fibers of two banana species, Kluai Hom Thong and Kluai Nam Wa were coated with micro wax at 0, 50, and 100 % of paraffin ...
Sopida Wisansakkul   +1 more
doaj   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Characterization of Emissions of Wax-Based Products During Combustion [PDF]

open access: yes, 2010
Currently, over 40% of the global burden of disease is attributed to environmental factors; of this, 2.6% of disease is attributed to indoor pollutants.
Albiston, Ben, Grasmick, Crystal
core   +1 more source

Generalized bioinspired approach to a daytime radiative cooling "skin"

open access: yes, 2020
Energy-saving cooling materials with strong operability are desirable towards sustainable thermal management. Inspired by the cooperative thermo-optical effect in fur of polar bear, we develop a flexible and reusable cooling skin via laminating a ...
Guo, Jing   +9 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Fabrication of Microfluidic Chips Based on an EHD-Assisted Direct Printing Method

open access: yesSensors, 2020
Microfluidic chips have been widely used in many areas such as biology, environmental monitoring, and micromixing. With the increasing popularity and complexity of microfluidic systems, rapid and convenient approaches for fabricating microfluidic chips ...
Xiang Chi   +6 more
doaj   +1 more source

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