Copper in cancer: friend or foe? Metabolism, dysregulation, and therapeutic opportunities
Abstract Copper, one of the essential nutrients for the human body, acts as an electron relay in multiple pathways due to its redox properties. Both deficiencies and excesses of copper lead to cellular fragility. Therefore, it can manifest pro‐ and anti‐cancer properties in tumors. Therefore, it is crucial to clarify the copper activity within the cell.
Dan Shan+13 more
wiley +1 more source
Laparoscopic management of paraganglioma in a pregnant woman: a case report
Introduction: Paraganglioma is an extremely rare catecholamine-producing tumor during pregnancy. Paraganglioma carries high risks of fetal and maternal mortality during pregnancy.
Mohammad Hadi Radfar+3 more
doaj +1 more source
'Case of the Month' from the University of Verona, Italy-navigating the medical and surgical challenges of urinary bladder paraganglioma: insights from a clinical case. [PDF]
BJU International, Volume 135, Issue 5, Page 743-747, May 2025.
Treccani LP+8 more
europepmc +2 more sources
Paraganglioma and pheochromocytoma upon maternal transmission of SDHD mutations [PDF]
The SDHD gene encodes a subunit of the mitochondrial tricarboxylic acid cycle enzyme and tumor ...
Bayley, J.P. (Jean-Pierre)+12 more
core +3 more sources
Malignant Gastric Paraganglioma with Liver Metastasis: Imaging Findings and Literature Review
Paraganglioma is a neuroendocrine tumor that grows in organs other than the adrenal gland and typically originates in the chromaffin cells, which are distributed along the regions of the sympathetic and parasympathetic branches of the nervous system in
Youe Ree Kim+2 more
doaj +1 more source
Genetics of Apparently Sporadic Pheochromocytoma and Paraganglioma in a Chinese Population [PDF]
© Georg Thieme Verlag KG Stuttgart New York.Identification of germline mutation in patients with apparently sporadic pheochromocytomas and paragangliomas is crucial.
Chen, SPL+11 more
core +1 more source
Teaching Point: A submucosal bladder wall lesion with high signal on T2-weighted MRI warrants blood and urine analysis to rule out a paraganglioma.
Degrieck, Bert+2 more
openaire +4 more sources
Paraganglioma is derived from the paraganglia tissue in the neck, along the sympathetic trunk, and in the pelvis. Paraganglioma has malignant potential and can metastasize to remote organs such as the liver, lungs, and bones. Most metachronous metastases
Run Yu+2 more
doaj +1 more source
An ectopic paraganglioma supplied by the subclavian artery in the right supraclavicular fossa
Paragangliomas are rare and highly vascularized neuroendocrine tumors originating from neural crest-derived paraganglionic tissue surrounding the autonomic nerve.
Yang Wang, MD+4 more
doaj
Pheochromocytoma – clinical manifestations, diagnosis and current perioperative management [PDF]
Pheochromocytoma is a neuroendocrine tumor characterized by the excessive production of catecholamines (epinephrine, norepinephrine, and dopamine). The diagnosis is suspected due to hypertensive paroxysms, associated with vegetative phenomena, due to the
Bratu, Ovidiu G+6 more
core +1 more source