Results 91 to 100 of about 55,383 (212)

Passaging of a Newcastle disease virus pigeon variant in chickens results in selection of viruses with mutations in the polymerase complex enhancing virus replication and virulence

, 2010
Some Newcastle disease virus (NDV) variants isolated from pigeons (pigeon paramyxovirus type 1; PPMV-1) do not show their full virulence potential for domestic chickens but may become virulent upon spread in these animals.
Peeters, B.P.H., Strategic Infection Biology, Dep Infectieziekten Immunologie, G. Koch, B. P. H. Peeters, Rottier, P.J.M., Dortmans, J.C.F.M., J. C. F. M. Dortmans, P. J. M. Rottier, Koch, G.   +9 more
core   +1 more source

Exploring inhibitor structural features required to engage the 216-loop of human parainfluenza virus type-3 hemagglutinin-neuraminidase

, 2017
Human parainfluenza virus type-3 is a leading cause of acute respiratory infection in infants and children. There is currently neither vaccine nor clinically effective treatment for parainfluenza virus infection.
Guillon, Patrice, El-Deeb, Ibrahim Mustafa, von Itzstein, Mark, Dirr, Larissa, El-Deeb, Ibrahim M   +4 more
core   +1 more source

Multivalent sialic acid binding proteins as novel therapeutics for influenza and parainfluenza infection

, 2014
In nature, proteins with weak binding affinity often use a multivalency approach to enhance protein affinity via an avidity effect. Interested in this multivalency approach, we have isolated a carbohydrate binding module (CBM) that recognises sialic ...
Alias, Nadiawati
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Isolation of a Parainfluenza Virus Type 3-like Agent from Guinea Pigs [PDF]

, 2001
Guinea pig (GP) sera seropositive to human parainfluenza virus type 3 (PIV-3) antigen were found previously in our laboratory. In the present study, we attempted to isolate and characterize a new agent from GP colonies.
Watanabe, Yoji, Ohsawa, Kazutaka, Miyata, Hironori, Sato, Hiroshi   +3 more
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Defective interfering particles of parainfluenza virus subtype 5 and interferon induction

, 2015
The innate immune response is the first line of defence against virus infection. Cells contain a diverse array of pathogen recognition receptors (PRRs) that are able to recognise multiple pathogen associated molecular patterns (PAMPS) that present ...
Short, John A. L.
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Exposing the Flexibility of Human Parainfluenza Virus Hemagglutinin-neuraminidase

, 2016
Human parainfluenza virus type 3 (hPIV-3) is a clinically significant pathogen and is the causative agent of pneumonia and bronchiolitis in children. In this study the solution dynamics of human parainfluenza type 3 hemagglutinin-neuraminidase (HN) have ...
Moritz Winger (1292721), Mark von Itzstein (373875)   +1 more
core   +1 more source

Retinoic acid inducible gene I Activates innate antiviral response against human parainfluenza virus type 3

Virology Journal, 2009
Human parainfluenza virus type 3 (HPIV3) is a respiratory paramyxovirus that infects lung epithelial cells to cause high morbidity among infants and children.
Bose Santanu, Sabbah Ahmed
doaj   +1 more source

Exposing the flexibility of human parainfluenza virus hemagglutinin- neuraminidase

, 2012
Human parainfluenza virus type 3 (hPIV-3) is a clinically significant pathogen and is the causative agent of pneumonia and bronchiolitis in children. In this study the solution dynamics of human parainfluenza type 3 hemagglutinin-neuraminidase (HN) have ...
Winger, Moritz, von Itzstein, Mark
core   +1 more source

Differential Effects of Parainfluenza Virus Type 3 on Human Monocytes and Dendritic Cells

Virology, 2001
To understand the lack of protective immunity observed after infection with parainfluenza virus type 3 (PIV3), we tested the effect of the virus on human monocytes and monocyte-derived immature dendritic cells (DCs). Expression of viral antigens on the cell surfaces correlated with replication of the virus, which was marginal in monocytes but extremely
Plotnicky-Gilquin, Hélène, Cyblat, Dominique, Aubry, Jean-Pierre, Delneste, Yves, Blaecke, Aline, Bonnefoy, Jean-Yves, Corvaı̈a, Nathalie, Jeannin, Pascale   +7 more
openaire   +2 more sources

Interferon, virus vaccines and antiviral drugs

, 2008
The emergence of viruses with zoonotic potential, i.e. with the potential ability to cross species barriers to infect unnatural hosts, poses a huge threat to humans.
Rodrigues, Ana Mara Lopes
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