Results 121 to 130 of about 55,383 (212)

Advanced in vitro and ex vivo models provide a suitable platform for the evaluation of antiviral small molecules against human parainfluenza virus 3

Human parainfluenza virus 3 (HPIV-3) is responsible for lower respiratory tract infections. Due to the lack of antiviral therapeutics or vaccines, infections can result in high mortality rates e.g., in immunocompromised patients.
Guillon, Patrice, Holt, Stephanie, Von Itzstein, Mark, Braun, Armin, Dahlmann, Franziska, Roepken, Fabian, El Deeb, Ibrahim M, Dirr, Larissa, Barbosa, Philippe Vollmer   +8 more
core   +1 more source

A robust mouse model of HPIV-3 infection and efficacy of GS-441524 against virus-induced lung pathology

Nature Communications
Human parainfluenza virus type 3 (HPIV-3) can cause severe respiratory tract infections. There are no convenient small-animal infection models. Here, we show viral replication in the upper and lower airways of AG129 mice (double IFNα/β and IFNγ receptor ...
Yuxia Lin, Mona Khan, Birgit Weynand, Manon Laporte, Frank Coenjaerts, Darius Babusis, John P. Bilello, Peter Mombaerts, Dirk Jochmans, Johan Neyts   +9 more
doaj   +1 more source

Nucleotide sequence of the human parainfluenza virus 3 matrix protein gene [PDF]

Nucleic Acids Research, 1987
K, Prinoski, M J, Côté, C Y, Kang, K, Dimock   +3 more
openaire   +2 more sources

Early and high Influenza A circulation alongside reduced Respiratory Syncytial Virus prevalence during autumn 2025 in paediatric patients attending emergency department. [PDF]

Ital J Pediatr
Di Maio VC, Scutari R, Ranno S, Coltella L, Cortazzo V, Colagrossi L, Vittucci AC, Antilici L, Linardos G, Salvatori A, Gentile L, Onori M, Lucignano B, Vrenna G, Pisani M, Cristaldi S, Raponi M, Russo C, Bernaschi P, Villani A, Perno CF.   +20 more
europepmc   +1 more source

Studies on interferon (IFN) induction and isolation of IFN-inducing mutant viruses

, 2011
The interferon (IFN) system is a powerful antiviral defense system. Host cell pattern recognition receptors (PRRs) recognise pathogen-associated molecule patterns (PAMPs) which when activated, lead to the transcription of the IFN-β gene. As a consequence
Chen, Shu
core  

Impact of immune status on respiratory virus prevalence and co-detection patterns: a retrospective analysis (2019-2024). [PDF]

BMC Pulm Med
Sahin EA, Caliskan E, Guzel Tunccan O, Tezer H, Fidan I, Caglar K, Bozdayi G.   +6 more
europepmc   +1 more source

Post-pandemic resurgence and co-detectiondynamics of respiratory pathogens revealed by syndromic multiplex PCR. [PDF]

BMC Microbiol
Aygar IS.
europepmc   +1 more source

Whole-Genome Phylogenetic Characterization of Human Parainfluenza Virus Type 4 Circulating in St. Petersburg, Russia. [PDF]

Viruses
Mansour O, Fadeev AV, Perederiy AA, Ksenafontov AD, Boyarintseva AY, Danilenko DM, Lioznov DA, Komissarov AB.   +7 more
europepmc   +1 more source

Honey as an antiviral agent against respiratory syncytial virus

, 2011
Respiratory syncytial virus is the most frequent cause of hospitalization for viral respiratory infections in infants and young children worldwide. It also severely affects immunocompromised adults and the elderly, however, despite decades of efforts ...
Zareie, Parvaneh Palma
core  

Acute Respiratory Failure and Ventilatory Support in Hospitalized Adults With Viral Respiratory Infection: A Retrospective Cohort Study. [PDF]

Open Forum Infect Dis
Neumann K, Jarlsdatter Hovind M, Berdal JE, Dalgard O, Leegaard TM, Ward Siljan W, Einvik G, Nakrem Lyngbakken M.   +7 more
europepmc   +1 more source