Results 101 to 110 of about 6,362,543 (296)
Parallel Deferred Update Replication
, 2013 Deferred update replication (DUR) is an established approach to implementing highly efficient and available storage. While the throughput of read-only transactions scales linearly with the number of deployed replicas in DUR, the throughput of update ...
Pacheco, Leandro +2 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Estimation of pure qubits on circles
, 2004 Gisin and Popescu [PRL, 83, 432 (1999)] have shown that more information about their direction can be obtained from a pair of anti-parallel spins compared to a pair of parallel spins, where the first member of the pair (which we call the pointer member ...
Akhiezer N I +9 more
core +4 more sources
Scientific American, 2003 18 pages, 8 figs. A less technical adaptation is scheduled for the May 2003 issue of Scientific American.
openaire +2 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Parallel containers: a tool for applying parallel computing applications on clusters [PDF]
, 2004 Parallel and cluster computing remain somewhat difficult to apply quickly for many applications domains. Recent developments in computer libraries such as the Standard Template Library of the C++ language and the Message Passing Package associated with
Gan-El, M., Hawick, K.A.
core
Journal of Symbolic Logic, 2003 AbstractWe consider combinatorial principles based on playing several two person games simultaneously. We call strategies for playing two or more games simultaneously parallel. The principles are easy consequences of the determinacy of games, in particular they are true for all finite games.
openaire +3 more sources
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source