Results 91 to 100 of about 2,671,885 (319)

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Parallel algorithms for series parallel graphs [PDF]

open access: yes, 1996
In this paper, a parallel algorithm is given that, given a graph G=(V, E), decides whether G is a series parallel graph, and if so, builds a decomposition tree for G of series and parallel composition rules. The algorithm uses O(log¦E¦log*¦E¦) time and O(¦E¦) operations on an EREW PRAM, andO(log¦E¦) time and O(¦E¦) operations on a CRCW PRAM (note that ...
Hans L. Bodlaender, Babette de Fluiter
openaire   +4 more sources

Robustness Analysis of Floating-Point Programs by Self-Composition

open access: yesJournal of Applied Mathematics, 2014
Robustness is a key property for critical systems that run in uncertain environments, to ensure that small input perturbations can cause only small output changes.
Liqian Chen   +4 more
doaj   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Parallel Computation in Econometrics: A Simplified Approach [PDF]

open access: yes
Parallel computation has a long history in econometric computing, but is not at all wide spread. We believe that a major impediment is the labour cost of coding for parallel architectures.
Neil Shephard   +2 more
core  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Automatically Tuning Parallel and Parallelized Programs [PDF]

open access: yes, 2010
In today's multicore era, parallelization of serial code is essential in order to exploit the architectures' performance potential. Parallelization, especially of legacy code, however, proves to be a challenge as manual efforts must either be directed towards algorithmic modifications or towards analysis of computationally intensive sections of code ...
Dave, Chirag, Eigenmann, Rudolf
openaire   +2 more sources

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

The quality of parallel imports [PDF]

open access: yes
This paper empirically analyzes the change in the quality of parallel import goods (goods that are traded without the permission of the intellectual property right holder) across countries over time.
Katherine M. Sauer
core  

Home - About - Disclaimer - Privacy