Results 141 to 150 of about 2,671,885 (319)
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Model Parallelism With Subnetwork Data Parallelism
CoRRPre-training large neural networks at scale imposes heavy memory demands on accelerators and often requires costly communication. We introduce Subnetwork Data Parallelism (SDP), a distributed training framework that partitions a model into structured subnetworks trained across workers without exchanging activations.
Vaibhav Singh +3 more
openaire +2 more sources
DynamicsThis work systematically addresses the dual challenges of non-inertial dynamic coupling and kinematic constraint redundancy encountered in dynamic modeling of serial–parallel–serial hybrid robotic mechanisms, and proposes an improved Newton–Euler ...
Qing Gu +5 more
doaj +1 more source
, 2008 Parallel was based on the simple idea that the everyday world is not what it seems. It featured art work that explored issues associated with the subconscious, the unknown, the paranormal and unseen energies and forces, inviting audiences to contemplate ...
Brigita Ozolins (14746069)
core
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Parallel combinator reduction : some performance bounds [PDF]
A parallel graph reduction machine simulator is described. This performs combinator reduction and can simulate various different parallel reduction strategies. A number of functional programs are examined, and experimental results presented comparing the
Joy, Mike, Axford, Tom
core
Rule Discovery with a Parallel Genetic Algorithm [PDF]
, 2000 An important issue in data mining is scalability with respect to the size of the dataset being mined. In the paper we address this issue by presenting a parallel GA for rule discovery.
Araujo, Dieferson L.A. +2 more
core
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Parallel Imports and Music CD Prices [PDF]
Parallel imports are a significant academic and policy issue. Official investigations into the impact of parallel imports on music CD prices have reached widely conflicting conclusions.
Yeh-ning Chen, Ivan Png
core
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source