Results 171 to 180 of about 2,671,885 (319)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Are We in Control? How Best to Include a Control Group in Interrupted Time Series Designs: A Simulation Study. [PDF]

J Eval Clin Pract
Manca F, Mackay D, Lewsey J.
europepmc   +1 more source

Parallel Kinematic Machines under Process Requirements

, 2006
this paper, the design of parallel machines is formulated in terms of a global constrained optimization problem, where the constraints are deduced from imperative process requirements e.g.
Andreas Pott, Parallel Kinematic Machines, Manfred Hiller   +2 more
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Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

A note on data-parallelism and (and-parallel) prolog

, 1994
Abstract is not available.
Hermenegildo, Manuel V., Carro Liñares, Manuel   +1 more
openaire   +1 more source

Biomechanical comparative analysis of multiple small diameter fan-shaped and parallel core decompression for early osteonecrosis of the femoral head. [PDF]

Front Bioeng Biotechnol
Yuan D, Qiu J, Yao Z, Wu C, Luo J, Ye C.
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Topological rules and anomalies in intramolecular G-quadruplex folding: a comprehensive study. [PDF]

Nucleic Acids Res
Granzhan A, Mouawad L.
europepmc   +1 more source

Characterisation based bottleneck analysis of parallel systems [PDF]

Bottleneck analysis plays an important role in the early design of parallel computers and programs. In this paper a methodology for bottleneck analysis based on an instruction level characterisation technique is presented. The methodology is based on the
Nudd, G. R., Zemerly, M. J., Papay, J.
core