Given the cost of trade and availability of pharmaceuticals, the driving force for parallel trade is the price difference between the source (exporting) and the destination (importing) country.
Granlund, David, Yesim Köksal, Miyase
core
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
A Double-Layer Parallel MEMS Inductor with Enhanced Current-Carrying Capacity and Thermal Stability. [PDF]
Micromachines (Basel)Pi X +7 more
europepmc +1 more source
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Ultrasound-Guided Humerus-Parallel Injectate Distribution to the Posterior Antebrachial Cutaneous Nerve-Related Fascial Plane and Common Extensor Origin: A Proof-of-Concept Cadaveric Anatomical Feasibility Study. [PDF]
Diagnostics (Basel)Kim SH +8 more
europepmc +1 more source
This paper revisits the logic of pursuing parallel R&D paths when there is uncertainty as to which approaches will succeed technically and/or economically. Previous findings by Richard Nelson and the present author are reviewed.
Scherer, F. M.
core
FEBS Open Bio, EarlyView.Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin +3 more
wiley +1 more source
Effects of Oral Berry Supplementation on Blood Pressure in Adults with Hypertension or Elevated Blood Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. [PDF]
NutrientsGuevara Guevara EV +8 more
europepmc +1 more source
Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source
Cumulant-Based Approaches for Testing the Assumption of Independent Errors in Non-Gaussian Parallel and Congeneric Measures. [PDF]
Educ Psychol MeasWiedermann W, Shi D.
europepmc +1 more source