Results 61 to 70 of about 3,741,686 (304)

Porting LASG/ IAP Climate System Ocean Model to Gpus Using OpenAcc

open access: yesIEEE Access, 2019
GPUs have become important solutions for accelerating scientific applications. Most of the existing work on climate models now use code rewritten using CUDA to achieve a limited speedup.
Jinrong Jiang   +8 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

PARALLEL IMPLEMENTATION OF THE METHOD OF GRADIENT BOOSTING

open access: yesСучасні інформаційні системи, 2018
The issue of machine learning has been paying more attention in all areas of information technology in recent times. On the one hand, this is due to the rapid growth of requirements for future specialists, and on the other - with the very rapid ...
Olena Tolstoluzka   +2 more
doaj   +1 more source

Recursive-Parallel Algorithm for Solving the Graph-Subgraph Isomorphism Problem

open access: yesМоделирование и анализ информационных систем, 2022
The paper proposes a parallel algorithm for solving the Graph-Subgraph Isomorphism Problem and makes an experimental study of its efficiency. The problem is one of the most famous NP-complete problems.
Vladimir V. Vasilchikov
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

A New Domain Decomposition Parallel Algorithm for Convection–Diffusion Problem

open access: yesMathematical Modelling and Analysis, 2014
Basing on overlapping domain decomposition, we construct a new parallel algorithm combined the method of subspace correction with least-squares procedure for solving time-dependent convection–diffusion problem. This algorithm is fully parallel.
Jiansong Zhang, Danping Yang
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

A parallel Viterbi decoder for block cyclic and convolution codes

open access: yes, 2005
We present a parallel version of Viterbi's decoding procedure, for which we are able to demonstrate that the resultant task graph has restricted complexity in that the number of communications to or from any processor cannot exceed 4 for BCH codes.
Amarasinghe, Kosala   +3 more
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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