Results 71 to 80 of about 127,054 (312)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

DEVELOPMENT OF A CORE THERMO-FLUID ANALYSIS CODE FOR PRISMATIC GAS COOLED REACTORS

open access: yesNuclear Engineering and Technology, 2014
A new computer code, named CORONA (Core Reliable Optimization and thermo-fluid Network Analysis), was developed for the core thermo-fluid analysis of a prismatic gas cooled reactor.
NAM-IL TAK   +4 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

iThreads: A Threading Library for Parallel Incremental Computation

open access: yes, 2015
International audienceIncremental computation strives for efficient successive runs of applications by re-executing only those parts of the computation that are affected by a given input change instead of recomputing everything from scratch.
Bhatotia, Pramod   +15 more
core   +1 more source

Parallel calculations by automata on direct and back spanning trees of a graph

open access: yesТруды Института системного программирования РАН, 2018
The paper presents a parallel computation algorithm of an arbitrary function value on a multiset of values distributed on directed graph vertices. The computation is performed by message passing executed by automata distributed on the graph vertices. The
Igor Burdonov   +2 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Structured Parallel Programming: patterns for efficient computation.

open access: yesJournal of Computer Science and Technology, 2015
In this book the authors, who are parallel computing experts and industry insiders, describe how to design and implement maintainable and efficient parallel algorithms using a pattern-based approach.
Armando Eduardo De Giusti
doaj  

Co-Processing Parallel Computation for Distributed Optical Fiber Vibration Sensing

open access: yesApplied Sciences, 2020
Rapid data processing is crucial for distributed optical fiber vibration sensing systems based on a phase-sensitive optical time domain reflectometer (Φ-OTDR) due to the huge amount of continuously refreshed sensing data.
Yu Wang   +6 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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