A telehealth approach to improving clinical trial access for infants with tuberous sclerosis complex [PDF]
Journal of Neurodevelopmental Disorders, 2020 Background Research in rare genetic syndromes associated with ASD is often hampered by the wide geographic distribution of families and the presence of medical comorbidities, such as epilepsy, that may preclude travel to clinical sites.
Carly Hyde +6 more
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A new randomization procedure based on multiple covariates and applicable to parallel studies with simultaneous enrollment of all subjects prior to intervention [PDF]
BMC Medical Research Methodology, 2020 Background Parallel intervention studies involving volunteers usually require a procedure to allocate the subjects to study-arms. Statistical models to evaluate the different outcomes of the study-arms will include study-arm as a factor along with any ...
Eric D. Schoen, Suzan Wopereis
doaj +4 more sources
Medical conditions at enrollment do not impact efficacy and safety of the adjuvanted recombinant zoster vaccine: a pooled post-hoc analysis of two parallel randomized trials [PDF]
Human Vaccines & Immunotherapeutics, 2019 In two pivotal efficacy studies (ZOE-50; ZOE-70), the adjuvanted recombinant zoster vaccine (RZV) demonstrated >90% efficacy against herpes zoster (HZ). Adults aged ≥50 or ≥70 years (ZOE-50 [NCT01165177]; ZOE-70 [NCT01165229]) were randomized to receive ...
Lidia Oostvogels +22 more
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Parallel enrollments: associations between university student life and performance
Cogent EducationAustria’s university system has no tuition fees and allows students to enroll in an unlimited number of programs simultaneously, regulated via legal measures to ensure fast and efficient studying and especially challenging those with more than one ...
Alexander Karl Ferdinand Loder +2 more
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Discover PsychologyCollege students are known to have high stress levels, which can have negative consequences on their academic performance. In Austria (Europe) there are no tuition fees and students are allowed to enroll in as many degree programs as they want ...
Alexander Karl Ferdinand Loder +2 more
doaj +2 more sources
Impact of Structured Patient Education and Outpatient Cardiac Rehabilitation Program on the Disability Profile of Conservatively Treated Medically Stable Postmyocardial Infarction Individuals: A Protocol [PDF]
Journal of Clinical and Diagnostic Research, 2021 Introduction: Cardiac rehabilitation and patient education are the two parallel components in the management of coronary heart disease. Although, it is recommended strongly to join an outpatient cardiac rehabilitation program, the enrollment rates are
Varoon Chandramohan Jaiswal +2 more
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Frontiers in Digital Health, 2021 Background: The COPD assessment test (CAT) is an 8-item questionnaire widely used in clinical practice to assess patient burden of disease. Digital health platforms that leverage electronic medication monitors (EMMs) are used to track the time and date ...
Leanne Kaye +4 more
doaj +1 more source
Encouraging early preventive dental visits for preschool‐aged children enrolled in Medicaid: using the Extended Parallel Process Model to conduct formative research [PDF]
Journal of Public Health Dentistry, 2012 AbstractObjective: Preventive dental visits for preschool‐aged children can result in better oral health outcomes, especially for children from lower income families. Many children, however, still do not see a dentist for preventive visits. This qualitative study examined the potential for the Extended Parallel Process Model (EPPM) to be used to ...
Natoshia M, Askelson +6 more
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How large must a dose‐optimization trial be?
CPT: Pharmacometrics & Systems Pharmacology, 2023 Recently promulgated Draft Guidance from the US Food and Drug Administration Oncology Center of Excellence (OCE) recommends randomized, parallel dose–response trials for “dose optimization,” but with vaguely stated aims that engage none of the ...
David C. Norris
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Nabilone for non-motor symptoms of Parkinson’s disease: a randomized placebo-controlled, double-blind, parallel-group, enriched enrolment randomized withdrawal study (The NMS-Nab Study) [PDF]
Journal of Neural Transmission, 2019 Although open-label observations report a positive effect of cannabinoids on non-motor symptoms (NMS) in Parkinson's disease (PD) patients, these effects remain to be investigated in a controlled trial for a broader use in NMS in PD patients. Therefore, we decided to design a proof-of-concept study to assess the synthetic cannabinoid nabilone for the ...
Marina Peball +9 more
openaire +2 more sources