Results 31 to 40 of about 1,337,477 (299)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

International Standards for Cross-Border Intellectual Property Protection: A Current Assessment of the Impact on Domestic Mechanisms

Московский журнал международного права
INTRODUCTION. This article examines the impact of the Agreement on Trade-Related Aspects of Intellectual Property Rights (TRIPS) on domestic legislation regarding the cross-border protection of intellectual property rights.
S. A. Agamagomedova
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Interaction of electronic declaration centers and customs posts of actual control in the conditions of legalization of parallel import

Вестник университета, 2023
This article studies the problems of the process of interaction of structural divisions of customs authorities on the example of electronic declaration centers and actual control posts in the conditions of legalization of parallel imports.
I. Yu. Sofiyannikova
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Specifics of foreign trade of the Russian Federation in the context of anti-Russian sanctions

Вестник университета
The relevance of this article is to assess the significant changes in the structure and directions of the Russian Federation’s (hereinafter referred to as RF, Russia) foreign trade activities over the past year and a half in connection with the special ...
A. V. Pasko, A. N. Gromova, A. S. Shashurina   +2 more
doaj   +1 more source

Salmonella enterica serovar typhi limits the potency of typhoid toxin and ADP‐ribosylating toxin AB to establish a persistent infection

FEBS Open Bio, EarlyView.
The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez, Juliette K. Tinker, Teresa Frisan, Taj Azarian, Ken Teter   +4 more
wiley   +1 more source

Parallel Imports and Music CD Prices [PDF]

Parallel imports are a significant academic and policy issue. Official investigations into the impact of parallel imports on music CD prices have reached widely conflicting conclusions.
Yeh-ning Chen, Ivan Png
core   +2 more sources

Limitations on Parallel Import of Medicinal Products: Comments in the Context of the Judgement of the Court of Justice of the European Union in Case C-602/19 Kohlpharma

Studia Iuridica Lublinensia, 2021
The judgement in case C-602/19 Kohlpharma is another decision of the Court of Justice of the European Union, which sets legal framework for marketing medicinal products from parallel import.
Jarosław Dudzik
doaj   +1 more source