Results 31 to 40 of about 110,234 (214)

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Optimization of Watt's Six-Bar Linkage to Generate Straight and Parallel Leg Motion

International Journal of Advanced Robotic Systems, 2012
This paper considers optimal synthesis of a special type of four-bar linkages. Combination of this optimal four-bar linkage with on of it's cognates and elimination of two redundant cognates will result in a Watt's six-bar mechanism, which generates ...
Hamid Mehdigholi, Saeed Akbarnejad
doaj   +1 more source

Quality of record linkage in a highly automated cancer registry that relies on encrypted identity data

GMS Medizinische Informatik, Biometrie und Epidemiologie, 2016
Objectives: In the absence of unique ID numbers, cancer and other registries in Germany and elsewhere rely on identity data to link records pertaining to the same patient. These data are often encrypted to ensure privacy.
Schmidtmann, Irene, Sariyar, Murat, Borg, Andreas, Gerold-Ay, Aslihan, Heidinger, Oliver, Hense, Hans-Werner, Krieg, Volker, Hammer, Gaël Paul   +7 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

A Parallel Multi-Party Privacy-Preserving Record Linkage Method Based on a Consortium Blockchain

Mathematics
Privacy-preserving record linkage (PPRL) is the process of linking records from various data sources, ensuring that matching records for the same entity are shared among parties while not disclosing other sensitive data.
Shumin Han, Zikang Wang, Dengrong Shen, Chuang Wang   +3 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

A novel prosthetic knee joint with a parallel spring and damping mechanism

International Journal of Advanced Robotic Systems, 2016
Prosthetic knee joint (PKJ) is an important apparatus for trans-femoral amputees to regain walking ability. This study has two objectives: (1) to design a high performance and low-cost passive PKJ and (2) to evaluate the performance of the PKJ.
Huiqun Fu, Xiufeng Zhang, Xitai Wang, Rong Yang, Jian Li, Li Wang, Ning Zhang, Guanglin Li, Tao Liu, Bingfei Fan, Yoshio Inoue   +10 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Topological Analysis of a Novel Compact Omnidirectional Three-Legged Robot with Parallel Hip Structures Regarding Locomotion Capability and Load Distribution

Robotics, 2021
In this study, a novel design for a compact, lightweight, agile, omnidirectional three-legged robot involving legs with four degrees of freedom, utilizing an spherical parallel mechanism with an additional non-redundant central support joint for the ...
David Feller, Christian Siemers
doaj   +1 more source