Results 81 to 90 of about 10,294 (296)
Orientational Capability Analysis of a 2UPR-SPR Parallel Manipulator
Jixie chuandong, 2019 The parallel module of Exechon machine tool is developed based on the 3 degree-of-freedom (DOF) 2UPR-SPR mechanism, which is a parallel spindle head with two rotational (orientational) DOFs and one translational DOF.
Che Linxian +3 more
doaj
MATEC Web of Conferences, 2016 Optimal point-to-point motion planning of flexible parallel manipulator was investigated in this paper and the 3RRR parallel manipulator is taken as the object.
Kong Minxiu, Chen Zhengsheng, Ji Chen
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Jixie chuandong, 2008 At singularities, the parallel manipulator will have more than one the motion trends. So the parallel manipulator will lose control. Based on the bifurcation characteristics of a parallel manipulator at singularities, a new method to estimate the losing ...
郭瑞琴
doaj
Parallel Manipulators with Lower Mobility [PDF]
, 2006 Parallel manipulators with lower mobility (LM-PMs) are multi-loop mechanisms with less than six degrees of freedom (dofs). This type of manipulators has attracted the attention both of academic researchers and of industries since the early appearance of the DELTA robot (Clavel 1988). The DELTA robot showed that, when the manipulation task requires less
openaire +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Advances in Mechanical Engineering, 2017 The Stewart platform is a typical parallel manipulator. It is used as a space docking mechanism whose requirement for movement scope is determinate. This article addresses the dimension synthesis of the space docking mechanism.
Zenghui Xie +3 more
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Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Optimization of 3-DOF parallel motion devices for low-cost vehicle simulators
Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2017 Motion generation systems are becoming increasingly important in certain Virtual Reality (VR) applications, such as vehicle simulators. This paper deals with the analysis of the Inverse Kinematics (IK) and the reachable workspace of a three-degrees-of ...
Sergio CASAS +3 more
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Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source