Results 61 to 70 of about 10,294 (296)

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

open access: yesFEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Control of a 3-DOF parallel wire driven stiffness-variable manipulator [PDF]

open access: yes, 2004
Parallel Wire Robot (PWR) is a bionic mechanism manipulator, whose flexibility of wires is similar to the compliance of human muscles. In this paper, a 3-dof Parallel Wire Driven (PWD) manipulator configuration is presented, and the modeling and the ...
Sui CP(隋春平), Zhao MY(赵明扬)
core  

Forward displacement analysis of a quadratic planar parallel manipulator:3-RPR parallel manipulator with similar triangular platforms [PDF]

open access: yes, 2009
A quadratic parallel manipulator refers to a parallel manipulator with a quadratic characteristic polynomial. This paper revisits the forward displacement analysis (FDA) of a quadratic parallel manipulator: 3-RPR planar parallel manipulator with similar ...
Gosselin, Clement M., Kong, Xianwen
core   +1 more source

Kinematic and Dynamic Analysis of the Partially Decoupled Parallel Manipulator

open access: yesJixie chuandong, 2022
Aiming at the machining of complex curved surface parts with parallel machine tools, a novel partially decoupled parallel manipulator (PM) is proposed. The degree of freedom and the decoupling performance of the mechanism are analyzed.
Canguo Zhang   +3 more
doaj  

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Development of a redundant robot manipulator based on three DOF parallel platforms [PDF]

open access: yes, 1995
In this paper, a ten degrees of freedom (DOF) redundant robot manipulator based on three DOF parallel platforms is introduced. The main contents of the paper include configuration, kinematics, mechanical design and control system.
Tan DL(谈大龙)   +4 more
core  

Design and Analysis of an Annular 3-PPR Planar Parallel Mechanism

open access: yesJixie chuandong, 2023
In order to enlarge the rotation workspace of the manipulator, an annular 3-PPR planar parallel mechanism with full rotation capability is proposed. Resorting to homogeneous transformation and closed vector method, the inverse kinematics solution of the ...
Wu Xiaoyong, Li Yiyi, Zhang Kaifei
doaj  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

A new methodology for designing PD controllers [PDF]

open access: yes, 2001
It is known that it is impossible to select fixed gains for a PD controller that will critically damp the response to disturbances for all configurations of a given robot system. Because of this the potential for overshoot is always present and cannot be
Atia, K.R., Cartmell, M.P., Cartmell, M.
core   +1 more source

Kinematic and Elastostatic Design Optimisation of the 3-DOF Gantry-Tau Parallel Kinematic Manipulator [PDF]

open access: yesModeling, Identification and Control, 2009
One of the main advantages of the Gantry-Tau machine is a large accessible workspace/footprint ratio compared to many other parallel machines. The Gantry-Tau improves this ration further by allowing a change of assembly mode without internal link ...
Ilya Tyapin, Geir Hovland
doaj   +1 more source

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