FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
An Enhanced Dynamic Model of a Spatial Parallel Mechanism Receiving Direct Constraints from the Base at Two Point-Contact Higher Kinematic Pairs. [PDF]
Biomimetics (Basel)Cheng C, Yuan X, Li Y.
europepmc +1 more source
Parallel Mechanisms. Kinematic Design of In-Parallel Actuated Mechanisms.
Journal of the Japan Society for Precision Engineering, 1997 openaire +2 more sources
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Comparisons of Inverse Dynamics Formulations in a Spatial Redundantly Actuated Parallel Mechanism Constrained by Two Point Contact Higher Kinematic Pairs. [PDF]
Biomimetics (Basel)Cheng C, Yuan X, Li Y, Liu J.
europepmc +1 more source
[Kinematics and workspace analysis of a spherical exoskeleton parallel mechanism]. [PDF]
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi, 2019 Zhao Y, Xia H, Yao Y, Li R.
europepmc +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
FEBS Open Bio, EarlyView.We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
A novel 3D parallel mechanism for the passive motion simulation of the patella-femur-tibia complex
, 2008 Parallel mechanisms have been exploited for the kinematic modelling of the passive motion, i.e. the motion under virtually unloaded conditions, of the patella-femur-tibia human joint. In particular, a new mechanism is devised in this paper: a 3D model of
PARENTI CASTELLI, VINCENZO +1 more
core
Design and Sensitivity Analysis Simulation of a Novel 3D Force Sensor Based on a Parallel Mechanism. [PDF]
Sensors (Basel), 2016 Yang EC.
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