Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Research on type synthesis of a new class of 2T1R uncoupled parallel mechanism with a suitable constraint branch. [PDF]
Song L +5 more
europepmc +1 more source
Parallel Mechanism of Spectral Feature-Enhanced Maps in EEG-Based Cognitive Workload Classification. [PDF]
Zhang Y, Shen Y.
europepmc +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
An Enhanced Dynamic Model of a Spatial Parallel Mechanism Receiving Direct Constraints from the Base at Two Point-Contact Higher Kinematic Pairs. [PDF]
Cheng C, Yuan X, Li Y.
europepmc +1 more source
Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke +4 more
wiley +1 more source
Comparisons of Inverse Dynamics Formulations in a Spatial Redundantly Actuated Parallel Mechanism Constrained by Two Point Contact Higher Kinematic Pairs. [PDF]
Cheng C, Yuan X, Li Y, Liu J.
europepmc +1 more source
[Kinematics and workspace analysis of a spherical exoskeleton parallel mechanism]. [PDF]
Zhao Y, Xia H, Yao Y, Li R.
europepmc +1 more source
Parallel Mechanisms. Kinematics and Dynamics of Parallel Mechanisms.
openaire +2 more sources
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source

