Results 151 to 160 of about 851,816 (312)
Design and Performance Evaluation of a Novel Wearable Parallel Mechanism for Ankle Rehabilitation. [PDF]
Front Neurorobot, 2020 Zuo S +5 more
europepmc +1 more source
Parallel Execution Fee Mechanisms
This paper investigates how pricing schemes can achieve efficient allocations in blockchain systems featuring multiple transaction queues under a global capacity constraint. I model a capacity-constrained blockchain where users submit transactions to different queues -- each representing a submarket with unique demand characteristics -- and decide to ...
openaire +2 more sources
Molecular Oncology, EarlyView.Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou +12 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Modelling of the human shoulder as a parallel mechanism without constraints
The synthesis of shoulder kinematics, either for simulation in a model or imitation in a robot, is a challenging task because of the contact between shoulder blade and ribcage. As the shoulder moves, the shoulder blade glides over the ribcage.
Terrier, Alexandre +4 more
core +1 more source
A New Type of Closed-loop Limb Redundant Parallel Mechanism
, 2019 Redundantly driven parallel mechanisms have been increasingly used in practical production because of their greater stiffness and force maneuverability. Based on 3-RPS parallel mechanism，a redundant parallel mechanism with five-bar closed-loop structure ...
Caiyou Qin, Juan Huang, Xiaoru Li
core +1 more source
Parallel Mechanism Composed of Abdominal Cuticles and Muscles Simulates the Complex and Diverse Movements of Honey Bee (Apis mellifera L.) Abdomen. [PDF]
J Insect Sci, 2020 Liang Y +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Kinetoelastodynamics Modeling and Analysis of Spatial Parallel Mechanism
, 2015 The nonlinear elastodynamic modeling and analysis of the 4-UPS-UPU spatial 5-degree-of-freedom parallel mechanism are investigated. The kinetoelastodynamics theory is used to derive the elastic dynamic equations of 4-UPS-UPU spatial parallel mechanism ...
Yunfeng Li +4 more
core +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source