Results 131 to 140 of about 851,816 (312)
Vibration Analysis of 2-PR(Pa)U- 2-PR(Pa)R New Parallel Mechanism [PDF]
International Journal of Advanced Design and Manufacturing Technology, 2018 Parallel kinematic machines, are closed loop structures which have more accuracy, stiffness and ability to withstand high loads. In this paper the vibration equations of the new parallel mechanism, that has higher stiffness because of parallelogram ...
Mehran Mahboubkhah +3 more
doaj
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Local search performance guarantees for restricted related parallel machine scheduling
We consider the problem of minimizing the makespan on restricted related parallel machines. In restricted machine scheduling each job is only allowed to be scheduled on a subset of machines. We study the worst-case behavior of local search algorithms. In
Recalde Diego +3 more
core
Data Parallel Performance Optimizations Using Array Aliasing
, 1999 The array aliasing mechanism provided in the Connection Machine Fortran (CMF) language and run{time system provides a unique way of identifying the memory address spaces local to processors within the global address space of distributed memory ...
Johnsson, Lennart,
core
, 2017 Human shoulder movements involve motions at four different articulations, one of which is the contact between the scapula bone and the ribcage. The shoulder biomechanical models become less reliable when the scapulothoracic (ST) contact, which is not a ...
Aibek S., Niyetkaliyev +9 more
core +1 more source
Parallel Mechanisms. Motion Control of Parallel Mechanism.
Journal of the Japan Society for Precision Engineering, 1997 TAKEO, Koji, KOSUGE, Kazuhiro
openaire +2 more sources
Molecular Oncology, EarlyView.Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Dynamics and control of a parallel mechanism for active vibration isolation in space station
, 2014 Vibration in the microgravity environment is with the characteristics of low frequency, small amplitude, and randomness. Control method of an active vibration isolation system with parallel mechanism applied to space application, which is effective for ...
Liu JG(刘金国) +4 more
core
Study on CNC System of Parallel Mechanism
, 2010 In this paper, the open architecture technique is used to develop the computer numerical control (CNC) system of parallel mechanism. The personal computer (PC) with high-performance motion control card Flex-6C and virtual instrument software package are ...
Xue Yong Zhong +3 more
core +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source