Results 51 to 60 of about 1,849,434 (247)
Nonlinear static and dynamic analysis of composite layered plates and shells using finite strip methods [PDF]
, 2003 In this thesis, a new concept of finite strip elements is introduced. Lagrangian, Hermitian and spline-type interpolations have been used independently along the two axes of the plate mid-plane.
Razzaq, Raja Javed
core +3 more sources
Guiding of keV ions between two insulating parallel plates
Scientific Reports, 2022 Experimental data are presented for low-energy singly charged ion transport between two insulating parallel plates. Using a beam intensity of approximately 20 pA, measurements of the incoming and transmitted beams provide quantitative temporal ...
R. D. DuBois, K. Tőkési, E. Giglio
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Molecular Oncology, EarlyView.LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Damage detections in nonlinear vibrating thermally loaded plates [PDF]
, 2010 In this work, geometrically nonlinear vibrations of fully clamped rectangular plates subjected to thermal changesare used to study the sensitivity of some vibration response parameters to the presence of damage and elevated temperature. The geometrically
Trendafilova, Irina, Manoach, Emil
core +3 more sources
AppliedMathIn this work, we investigate isothermal MHD motions of a large class of rate type fluids through a porous medium between two infinite horizontal parallel plates when a differential expression of the non-trivial shear stress is prescribed on the boundary.
Constantin Fetecau +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis +20 more
wiley +1 more source
NLO radiative correction to the Casimir energy in Lorentz-violating scalar field theory
Nuclear Physics B, 2019 Violation of the Lorentz symmetry has important effects on physical quantities including field propagators. Therefore, in addition to the leading order, the sub-leading order of quantities may be modified. In this paper, we calculate the next to leading (
Amirhosein Mojavezi +2 more
doaj +1 more source