Results 51 to 60 of about 3,995,471 (311)

A Formal Model For Real-Time Parallel Computation

open access: yes, 2012
The imposition of real-time constraints on a parallel computing environment- specifically high-performance, cluster-computing systems- introduces a variety of challenges with respect to the formal verification of the system's timing properties.
Chikkagoudar, Satish, Hui, Peter
core   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Tentatives d’accommodement et justice parallèle à Lyon dans la seconde moitié du xviiie siècle. L’enseignement des archives judiciaires

open access: yesL'Atelier du CRH, 2009
In Lyon society under the Old Regime, settling a dispute by mutual agreement through arbitration was a mechanism which contributed to creating household equilibrium.
Marc Vacher
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Editorial: Special Issue on «Advanced Computing: from Theory to Practice»

open access: yesТруды Института системного программирования РАН, 2019
This special issue contains selected papers that had been submitted to Proceedings of the Institute for System Programming of the Russian Academy of Sciences.
Andrei Tchernykh, Allel Hadjali
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Introduction of mixed forms of education based on the digital and analog kinds integration of the organization of the educational process of universities

open access: yesВестник университета, 2021
The abrupt transition to the distance learning format during the COVID-19 pandemic showed that the legal framework for regulating the introduction of new digital telecommunications technologies is largely lagging behind in educational organizations, and ...
P. V. Tereliansky   +2 more
doaj   +1 more source

Analytic approximations, perturbation theory, effective field theory methods and their applications

open access: yes, 2014
We summarize the parallel session B4: 'Analytic approximations, perturbation theory effective field theory methods and their applications' and the joint session B2/B4: 'Approximate solutions to Einstein equations: Methods and Applications', of the GR20 &
Cardoso, Vitor, Porto, Rafael A.
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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