Results 71 to 80 of about 1,454,309 (287)
Stellar populations in the Magellanic Clouds: looking through the dust
, 2007 We present the first results of our study of stellar populations in the Large and Small Magellanic Clouds based on multi-band WFPC2 observations of "random" fields taken as part of the "pure parallel" programme carried out with the HST as a service to ...
De Marchi +4 more
core +2 more sources
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
On Lorentz spacetimes of constant curvature
, 2015 We describe in parallel the Lorentzian homogeneous spaces $G=\mathrm{PSL}(2,\mathbb{R})$ and $\mathfrak{g}=\mathfrak{psl}(2,\mathbb{R})$, and review some recent results relating the geometry of their quotients by discrete groups.Comment: 16 pages, 2 ...
Guéritaud, François
core +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Conflicts of Criminal Jurisdiction in the European Union
Bergen Journal of Criminal Law and Criminal Justice, 2015 Conflicts of criminal jurisdiction between the Member States belong to the most difficult challenges that the European Union has to face in order to establish a true “area of freedom, security and justice”.
Frank Zimmermann
doaj +1 more source
Gleichberechtigung in erster Instanz – Scheidungsurteile der 1950er Jahre im Ost-/West-Vergleich
Právněhistorické studie, 2020 Two German constitutions led to exceptional circumstances in German family law of the1950s: the principle of gender equality according to Art. 7 Abs. 1 GDR-Constitution and Art. 3 Abs. 2 of the Western German “Basic Law” invalidated all other conflicting
Raphaela Etzold
doaj +1 more source
PPF - A Parallel Particle Filtering Library
, 2014 We present the parallel particle filtering (PPF) software library, which enables hybrid shared-memory/distributed-memory parallelization of particle filtering (PF) algorithms combining the Message Passing Interface (MPI) with multithreading for multi ...
Demirel, Ömer +4 more
core +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Multilingual Models for Compositional Distributed Semantics
, 2014 We present a novel technique for learning semantic representations, which extends the distributional hypothesis to multilingual data and joint-space embeddings.
Blunsom, Phil, Hermann, Karl Moritz
core +1 more source