Results 81 to 90 of about 1,454,309 (287)
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Frontiers in Genetics, 2016 Adopting the interpretative/hermeneutical method typical of much legal scholarship, this article considers two sets of issues pertaining to LTDNA profiles as evidence in criminal proceedings.
Paul Roberts, Paul Roberts, Paul Roberts
doaj +1 more source
PKind: A parallel k-induction based model checker
, 2011 PKind is a novel parallel k-induction-based model checker of invariant properties for finite- or infinite-state Lustre programs. Its architecture, which is strictly message-based, is designed to minimize synchronization delays and easily accommodate the ...
Kahsai, Temesghen, Tinelli, Cesare
core +2 more sources
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Arbitration in Romania: Looking good, hoping for more [PDF]
Strani pravni životThis paper provides a current overview of the arbitration legal framework in Romania, analysing the historic development of an arbitration friendly jurisdiction.
Alexe Cristina, Șoimulescu Oana
doaj +1 more source
Supersymmetry, replica and dynamic treatments of disordered systems: a parallel presentation
, 2002 I briefly review the three nonperturbative methods for the treatment of disordered systems -- supersymmetry, replicas and dynamics -- with a parallel presentation that highlights their connections and differences.Comment: Proceedings of the Inhomogeneous
Kurchan, Jorge
core
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
“Making reality come true”. Literature and Politics
Between, 2015 The present issue of Between contains the proceedings of the 2014 Compalit annual conference, The Political Imaginary: Commitment, Resistance, Ideology (Bologna, 17-19 December 2014).
Silvia Albertazzi +4 more
doaj +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source